Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | ANPEP | P15144 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1004861 | 0.83 | PTPN1 (0.35) | MMP2ANPEPBRD4KDM4ETSHR | |
| SCHEMBL1004592 | 0.78 | MMP2 (0.37) | MMP2ANPEPBRD4KMT2ACYP1A2 | |
| SCHEMBL1007354 | 0.77 | FKBP1A (0.39) | MMP2ANPEPTSHRKMT2AALDH1A1 | |
| SCHEMBL17448552 | 0.70 | MMP2 (0.37) | MMP2ANPEPBRD4KDM4ETSHR | |
| SCHEMBL13738649 | 0.70 | MMP2 (0.37) | MMP2ANPEPBRD4KDM4ETSHR | |
| SCHEMBL29388224 | 0.65 | KMT2A (0.49) | MMP2ANPEPBRD4TSHRKMT2A | |
| SCHEMBL17136885 | 0.65 | MMP2 (0.41) | MMP2ANPEPBRD4KDM4ETSHR | |
| SCHEMBL13739598 | 0.65 | KMT2A (0.49) | MMP2ANPEPBRD4TSHRKMT2A | |
| SCHEMBL17136874 | 0.64 | ACE (0.46) | MMP2ANPEPBRD4KMT2ACYP1A2 | |
| SCHEMBL17442799 | 0.63 | DRD2 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011330-A2 | INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACOR INC. (US) | 2011-01-27 | — | — | WO | disclosed |