Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL522532 | 0.95 | SLC6A3 (0.44) | SLC6A3SLC6A2SLC6A4CHRM2HTR1A | |
| SCHEMBL522530 | 0.91 | CYP19A1 (0.41) | SLC6A3CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL10046459 | 0.88 | PTAFR (0.42) | SLC6A3CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL522353 | 0.86 | PTAFR (0.47) | SLC6A3ADRA1ATSHROPRM1SMN1; SMN2 | |
| SCHEMBL10046467 | 0.85 | ALDH1A1 (0.42) | ADRA1AKCNH2TDP1NPSR1OPRM1 | |
| SCHEMBL10046465 | 0.83 | OPRM1 (0.44) | OPRM1CYP19A1OPRD1OPRK1OPRL1 | |
| SCHEMBL521671 | 0.81 | PTAFR (0.45) | CYP2C19OPRM1ALDH1A1CYP3A4OPRD1 | |
| SCHEMBL10046462 | 0.81 | PTAFR (0.44) | DRD3OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL10046472 | 0.79 | OPRK1 (0.45) | SLC6A3SLC6A2SLC6A4CHRM2ADRA2A | |
| SCHEMBL10046461 | 0.78 | OPRL1 (0.45) | SLC6A3CYP2D6TSHRCYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029041-A1 | 2-ARYL IMIDAZOLINE DERIVATIVES | MSD K.K. (JP) | 2012-02-02 | — | — | US | disclosed |
| US-20120029041-A1 | 2-ARYL IMIDAZOLINE DERIVATIVES | MSD K.K. (JP) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029041-A1 | 2-ARYL IMIDAZOLINE DERIVATIVES | CLIC1, NAT1, NMRAL1 | SLC6A3 864/4885SLC6A2 2028/4885SLC6A4 2610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.