SCHEMBL522532

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10046470	0.95	SLC6A3 (0.47)	SLC6A3SLC6A2SLC6A4CHRM2HTR1A
	SCHEMBL10046459	0.89	PTAFR (0.42)	SLC6A3CHRM2ADRA2ACHRM1DRD1
	SCHEMBL522530	0.89	CYP19A1 (0.41)	SLC6A3CHRM2ADRA2ACHRM1DRD1
	SCHEMBL521671	0.85	PTAFR (0.45)	PTAFRCYP2C19OPRM1OPRD1OPRK1
	SCHEMBL10046462	0.85	PTAFR (0.44)	DRD3PTAFRCA1CA2CA4
	SCHEMBL522353	0.84	PTAFR (0.47)	SLC6A3ADRA1APTAFRTSHRPTGS2
	SCHEMBL10046463	0.82	OPRD1 (0.50)	KCNH2CYP2D6TSHRCYP2C19NPSR1
	SCHEMBL10046461	0.82	OPRL1 (0.45)	SLC6A3PTAFRCYP2D6TSHRCYP2C19
	SCHEMBL10046465	0.81	OPRM1 (0.44)	OPRM1OPRD1OPRK1OPRL1CYP19A1
	SCHEMBL522607	0.81	OPRK1 (0.43)	PTAFRCYP2D6OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.