Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1004825 | 0.81 | CYP2C19 (0.33) | LMNACYP2C19ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11500737 | 0.74 | CYP2D6 (0.41) | CYP2C19KMT2ARECQLMAPK1 | |
| SCHEMBL16128977 | 0.74 | CYP2D6 (0.42) | LMNATDP1L3MBTL1CYP2C19CES2 | |
| SCHEMBL2152870 | 0.74 | ALDH1A1 (0.43) | LMNAL3MBTL1CYP2C19ALDH1A1MAPT | |
| SCHEMBL776296 | 0.73 | CYP2C19 (0.36) | LMNATDP1CYP2C19ALDH1A1MAPT | |
| SCHEMBL776368 | 0.73 | CYP2C19 (0.36) | LMNATDP1CYP2C19ALDH1A1MAPT | |
| SCHEMBL122869 | 0.71 | ADRA2C (0.39) | LMNATDP1L3MBTL1CYP2C19CES2 | |
| SCHEMBL7206079 | 0.70 | LMNA (0.35) | LMNATDP1CYP2C19ALDH1A1MAPT | |
| SCHEMBL776369 | 0.70 | CYP2C19 (0.34) | LMNACYP2C19ALDH1A1MAPTKDM4E | |
| SCHEMBL9112613 | 0.68 | KDM4E (0.33) | LMNATDP1CYP2C19ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883912-B2 | Synthesis of arborescent polymers via controlled inimer-type reversible addition-fragmentation chain transfer (RAFT) polymerization | UNIVERSITY OF AKRON (US) | 2014-11-11 | — | — | US | disclosed |
| US-20110144268-A1 | SYNTHESIS OF ARBORESCENT POLYMERS VIA CONTROLLED INIMER-TYPE REVERSIBLE ADDITION-FRAGMENTATION CHAIN TRANSFER (RAFT) POLYMERIZATION | THE UNIVERSITY OF AKRON (US) | 2011-06-16 | — | — | US | disclosed |
| US-7714075-B1 | Polymerization with living characteristics | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2010-05-11 | — | — | US | disclosed |
| US-7666962-B2 | Polymerization with living characteristics | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2010-02-23 | — | — | US | disclosed |
| WO-2010019563-A1 | SYNTHESIS OF ARBORESCENT POLYMERS VIA CONTROLLED INIMER-TYPE REVERSIBLE ADDITION-FRAGMENTATION CHAIN TRANSFER (RAFT) POLYMERIZATION | THE UNIVERSITY OF AKRON (US) | 2010-02-18 | — | — | WO | disclosed |
| US-7662986-B2 | Polymerization with living characteristics | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2010-02-16 | — | — | US | disclosed |
| US-20080139836-A1 | Polymerization with living characteristics | LE TAM PHUONG | 2008-06-12 | — | — | US | disclosed |
| US-20080139764-A1 | Polymerization with living characteristics | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2008-06-12 | — | — | US | disclosed |
| US-7250479-B2 | Polymerization with living characteristics | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-07-31 | — | — | US | disclosed |
| US-20040171777-A1 | Polymerization with living characteristics | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2004-09-02 | — | — | US | disclosed |
| EP-0910587-B1 | POLYMERIZATION WITH LIVING CHARACTERISTICS | DU PONT (US) | 2001-12-12 | — | — | EP | disclosed |
| EP-0910587-A1 | POLYMERIZATION WITH LIVING CHARACTERISTICS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-04-28 | — | — | EP | disclosed |
| WO-1998001478-A1 | POLYMERIZATION WITH LIVING CHARACTERISTICS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139836-A1 | Polymerization with living characteristics | UQCRB, MTR, UQCRC2 | LMNA 3210/4885AKT1 4304/4885TDP1 3668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.