SCHEMBL10051130

SCHEMBL10051130

C=C(C)C(=O)NCCOCC(O)CO

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.42
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TGFBR1 P36897 1/20 0.39
PLA2G2C Q5R387 1/20 0.37
THRB P10828 1/20 0.33
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP14 P50281 1/20 0.32
KDM4E B2RXH2 1/20 0.32
DUSP3 P51452 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10051133 0.86 TGFBR1 (0.35) USP2MEN1KMT2ATGFBR1PLA2G2C
SCHEMBL15935691 0.84 USP2 (0.46) USP2MEN1KMT2APLA2G2CKDM4E
SCHEMBL24462897 0.84 USP2 (0.46) USP2MEN1KMT2APLA2G2CKDM4E
SCHEMBL867377 0.81 TSHR (0.46) MEN1KMT2ATGFBR1THRBMMP9
SCHEMBL12036308 0.80 MEN1 (0.47) MEN1KMT2ATGFBR1THRBLMNA
SCHEMBL3510614 0.79 USP2 (0.43) USP2MEN1KMT2APLA2G2CKDM4E
SCHEMBL18141154 0.79 TGFBR1 (0.43) TGFBR1PLA2G2CTHRB
SCHEMBL23049027 0.78 THRB (0.38) MEN1KMT2ATGFBR1THRBTSHR
SCHEMBL13790899 0.78 MEN1 (0.33) MEN1KMT2ATHRBMMP9MMP8
SCHEMBL10051131 0.78 MEN1 (0.36) MEN1KMT2ATHRBMMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987410-B2 Terminal unsaturated, glycidol-based macromonomers, polymers obtainable therefrom, preparation and use BYK-CHEMIE GMBH (DE) 2015-03-24 US disclosed
US-20120165414-A1 TERMINAL UNSATURATED, GLYCIDOL-BASED MACROMONOMERS, POLYMERS OBTAINABLE THEREFROM, PREPARATION AND USE BYK-CHEMIE GMBH (DE) 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165414-A1 TERMINAL UNSATURATED, GLYCIDOL-BASED MACROMONOMERS, POLYMERS OBTAINABLE THEREFROM, PREPARATION AND USE OXER1, OXGR1, ACSL3 USP2 2076/4885MEN1 3020/4885KMT2A 2609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.