SCHEMBL10051133

SCHEMBL10051133

C=C(C)C(=O)NCCOCC(COCC(CO)OCC(O)CO)OCC(O)CO

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.35
USP2 O75604 1/20 0.35
PLA2G2C Q5R387 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10051130 0.86 USP2 (0.42) TGFBR1USP2PLA2G2CMEN1KMT2A
SCHEMBL6025190 0.75 USP2 (0.48) USP2
SCHEMBL16746550 0.75 MMP9 (0.45)
SCHEMBL23049027 0.73 THRB (0.38) TGFBR1MEN1KMT2A
SCHEMBL10453102 0.73 USP2 (0.44) USP2MEN1KMT2A
SCHEMBL16134391 0.72 USP2 (0.42) USP2MEN1KMT2A
SCHEMBL10051131 0.72 MEN1 (0.36) MEN1KMT2A
SCHEMBL15935691 0.72 USP2 (0.46) USP2PLA2G2CMEN1KMT2A
SCHEMBL24462897 0.72 USP2 (0.46) USP2PLA2G2CMEN1KMT2A
SCHEMBL867377 0.72 TSHR (0.46) TGFBR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987410-B2 Terminal unsaturated, glycidol-based macromonomers, polymers obtainable therefrom, preparation and use BYK-CHEMIE GMBH (DE) 2015-03-24 US disclosed
US-8987410-B2 Terminal unsaturated, glycidol-based macromonomers, polymers obtainable therefrom, preparation and use BYK-CHEMIE GMBH (DE) 2015-03-24 US disclosed
EP-2443170-B1 TERMINAL UNSATURATED, GLYCIDOL BASED MACROMONOMERS, POLYMERS OBTAINABLE THEREFROM, PRODUCTION AND USE THEREOF BYK CHEMIE GMBH (DE) 2013-04-03 EP disclosed
US-20120165414-A1 TERMINAL UNSATURATED, GLYCIDOL-BASED MACROMONOMERS, POLYMERS OBTAINABLE THEREFROM, PREPARATION AND USE BYK-CHEMIE GMBH (DE) 2012-06-28 US disclosed
US-20120165414-A1 TERMINAL UNSATURATED, GLYCIDOL-BASED MACROMONOMERS, POLYMERS OBTAINABLE THEREFROM, PREPARATION AND USE BYK-CHEMIE GMBH (DE) 2012-06-28 US disclosed
WO-2010145761-A1 TERMINAL UNSATURATED, GLYCIDOL BASED MACROMONOMERS, POLYMERS OBTAINABLE THEREFROM, PRODUCTION AND USE THEREOF BYK-CHEMIE GMBH (DE) 2010-12-23 WO disclosed
EP-2264082-A1 Terminal unsaturated glycidol-based marcomonomers, polymers obtained from them, manufacture and use BYK-Chemie GmbH (DE) 2010-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165414-A1 TERMINAL UNSATURATED, GLYCIDOL-BASED MACROMONOMERS, POLYMERS OBTAINABLE THEREFROM, PREPARATION AND USE OXER1, OXGR1, ACSL3 TGFBR1 1915/4885USP2 2076/4885PLA2G2C 3398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.