SCHEMBL10051131

SCHEMBL10051131

C=C(C)C(=O)NCCOCC(O)COC(C)OCC

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
THRB P10828 1/20 0.33
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP14 P50281 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10051130 0.78 USP2 (0.42) MEN1KMT2ATHRBLMNAMMP9
SCHEMBL867377 0.76 TSHR (0.46) MEN1KMT2ATHRBLMNAMMP9
SCHEMBL13790899 0.76 MEN1 (0.33) MEN1KMT2ATHRBHSD17B10MMP9
SCHEMBL151135 0.74 THRB (0.57) MEN1KMT2ATHRBALDH1A1
SCHEMBL19757251 0.74 LMNA (0.55) THRBLMNAHSD17B10TDP1
SCHEMBL1123354 0.72 EPHX2 (0.44) MEN1KMT2ATHRBALDH1A1
SCHEMBL20613893 0.72 LPAR5 (0.38) MMP9MMP8MMP14ALDH1A1
SCHEMBL29518886 0.72 TDP1 (0.49) MEN1KMT2ATHRBHSD17B10TDP1
SCHEMBL10051133 0.72 TGFBR1 (0.35) MEN1KMT2A
SCHEMBL12036308 0.72 MEN1 (0.47) MEN1KMT2ATHRBLMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987410-B2 Terminal unsaturated, glycidol-based macromonomers, polymers obtainable therefrom, preparation and use BYK-CHEMIE GMBH (DE) 2015-03-24 US disclosed
US-20120165414-A1 TERMINAL UNSATURATED, GLYCIDOL-BASED MACROMONOMERS, POLYMERS OBTAINABLE THEREFROM, PREPARATION AND USE BYK-CHEMIE GMBH (DE) 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165414-A1 TERMINAL UNSATURATED, GLYCIDOL-BASED MACROMONOMERS, POLYMERS OBTAINABLE THEREFROM, PREPARATION AND USE OXER1, OXGR1, ACSL3 MEN1 3020/4885KMT2A 2609/4885THRB 2712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.