Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MGMT | P16455 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16063177 | 0.79 | MAPT (0.41) | MAPTADAM17KMT2AATM | |
| SCHEMBL10024498 | 0.74 | PDE7A (0.42) | MAPTADAM17KMT2AATM | |
| SCHEMBL16062750 | 0.69 | HPD (0.30) | — | |
| SCHEMBL10024485 | 0.65 | TSHR (0.43) | MAPTADAM17KMT2AATM | |
| SCHEMBL10024451 | 0.64 | PDE7A (0.40) | MAPTKMT2A | |
| SCHEMBL10024450 | 0.63 | TSHR (0.46) | MAPTADAM17KMT2AATM | |
| SCHEMBL10024500 | 0.63 | TP53 (0.43) | MAPTKMT2A | |
| SCHEMBL8106323 | 0.62 | KMT2A (0.37) | MAPTKMT2AMGMT | |
| SCHEMBL28339719 | 0.60 | ALDH1A1 (0.58) | KMT2A | |
| SCHEMBL13479393 | 0.60 | GPR35 (0.60) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120052488-A1 | PHOTODAMAGE MITIGATION COMPOUNDS AND SYSTEMS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| WO-2012021733-A2 | PHOTODAMAGE MITIGATION COMPOUNDS AND SYSTEMS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052488-A1 | PHOTODAMAGE MITIGATION COMPOUNDS AND SYSTEMS | CRY1, ERCC1, ERCC4 | MAPT 518/4885ADAM17 3274/4885KMT2A 2469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.