Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1189292 | 1.00 | SIGMAR1 (0.68) | SIGMAR1POLBMAPK1TRPA1BCHE | |
| SCHEMBL1005591 | 1.00 | SIGMAR1 (0.68) | SIGMAR1POLBMAPK1TRPA1BCHE | |
| SCHEMBL1752567 | 0.89 | SIGMAR1 (0.59) | SIGMAR1POLBMAPK1BCHELMNA | |
| SCHEMBL31127843 | 0.84 | SIGMAR1 (0.63) | SIGMAR1POLBMAPK1BCHEGAA | |
| SCHEMBL536907 | 0.84 | SIGMAR1 (0.63) | SIGMAR1POLBMAPK1BCHEGAA | |
| N-Benzylamphetamine SCHEMBL2451256 | 0.81 | SIGMAR1 (1.00) | SIGMAR1POLBMAPK1LMNATAAR1 | |
| SCHEMBL172633 | 0.81 | SIGMAR1 (0.70) | SIGMAR1POLBMAPK1BCHELMNA | |
| N-Benzylamphetamine SCHEMBL2795222 | 0.81 | SIGMAR1 (1.00) | SIGMAR1POLBMAPK1LMNATAAR1 | |
| N-Benzylamphetamine SCHEMBL2798189 | 0.81 | SIGMAR1 (1.00) | SIGMAR1POLBMAPK1LMNATAAR1 | |
| SCHEMBL13675825 | 0.81 | SIGMAR1 (0.70) | SIGMAR1POLBMAPK1BCHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218849-B | Process for the preparation of amines | 巴斯夫欧洲公司 | 2023-08-18 | — | — | CN | claimed |
| US-11390578-B2 | Method for synthesizing amines | BASF SE (DE) | 2022-07-19 | — | — | US | claimed |
| EP-3774716-B1 | PROCESS FOR THE PREPARATION OF AMINES | BASF SE (DE) | 2022-03-16 | — | — | EP | claimed |
| US-20210155574-A1 | METHOD FOR SYNTHESIZING AMINES | BASF SE (DE) | 2021-05-27 | — | — | US | claimed |
| EP-3774716-A1 | METHOD FOR SYNTHESIZING AMINES | BASF SE (DE) | 2021-02-17 | — | — | EP | claimed |
| CN-112218849-A | Process for preparing amines | 巴斯夫欧洲公司 | 2021-01-12 | — | — | CN | claimed |
| WO-2019192903-A1 | METHOD FOR SYNTHESIZING AMINES | BASF SE (DE) | 2019-10-10 | — | — | WO | claimed |
| EP-0301925-B1 | PROCESS FOR THE ENANTIOSPECIFIC PREPARATION OF (S)2-ETHYL AMINO-1-3-(TRIFLUOROMETHYL PHENYL) PROPANE | ADIR ET COMPAGNIE (FR) | 1991-10-23 | — | — | EP | claimed |
| EP-3560932-B1 | PROCESS FOR PREPARING 7H-PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AND SYNTHETIC INTERMEDIATES OF SAME | JAPAN TOBACCO INC (JP) | 2026-03-11 | — | — | EP | disclosed |
| US-12319679-B2 | Morpholinyl, piperazinyl, oxazepanyl and diazepanyl O-glycoprotein-2-acetamido-2-deoxy-3-d-glucopyranosidase inhibitors | BIOGEN MA INC. (US) | 2025-06-03 | — | — | US | disclosed |
| US-20250084106-A1 | PROCESS FOR PREPARING 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES AND SYNTHETIC INTERMEDIATES THEREOF | LEO PHARMA A/S (DK) | 2025-03-13 | — | — | US | disclosed |
| US-20250066313-A1 | Methods of Synthesis of Chiral 3,5-Disubstituted Morpholine Compounds and Intermediates Useful Therein | BEONE MEDICINES I GMBH (CH) | 2025-02-27 | — | — | US | disclosed |
| US-12195481-B2 | Process for preparing 7H-pyrrolo[2,3-d]pyrimidine derivatives and synthetic intermediates thereof | JAPAN TOBACCO INC. (JP) | 2025-01-14 | — | — | US | disclosed |
| CN-118317943-A | Synthesis method of chiral 3, 5-disubstituted morpholine compound and useful intermediate thereof | 百济神州有限公司 | 2024-07-09 | — | — | CN | disclosed |
| EP-0044984-A1 | Process for the optical resolution of mixtures of d- and l-2-(6-methoxy-2-naphthyl)-propionic acids, the cinchonidine salt of d-2-(6-methoxy-2-naphthyl)-propionic acid and the preparation thereof | ALFA FARMACEUTICI S.p.A. (IT) | 1982-02-03 | — | — | EP | disclosed |
| US-4247498-A | THERMOPLASTICS | AKZONA INCORPORATED (US) | 1981-01-27 | — | — | US | disclosed |
| US-4246164-A | SALT FORMATION WITH N-METHYL-D-GLUCAMINE | SYNTEX CORPORATION (PA) | 1981-01-20 | — | — | US | disclosed |
| US-4239912-A | SALT FORMATION | AMERICAN CYANAMID COMPANY (US) | 1980-12-16 | — | — | US | disclosed |
| EP-0007116-A1 | Method for resolving racemic 6-methoxy-alpha-methyl-2-naphthalene acetic acid into its enantiomers and resolving medium | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1980-01-23 | — | — | EP | disclosed |
| US-3998827-A | HYPOTENSIVE AGENTS | THE UPJOHN COMPANY (US) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11390578-B2 | Method for synthesizing amines | PNMT, ADH1A, ADH1C | SIGMAR1 1209/4885POLB 731/4885MAPK1 2036/4885 |
| US-12319679-B2 | Morpholinyl, piperazinyl, oxazepanyl and diazepanyl O-glycoprotein-2-acetamido-2-deoxy-3-d-glucopyranosidase inhibitors | MAN2A1, MAN2B2, MGAT3 | SIGMAR1 2022/4885POLB 3038/4885MAPK1 2547/4885 |
| US-12195481-B2 | Process for preparing 7H-pyrrolo[2,3-d]pyrimidine derivatives and synthetic intermediates thereof | JAK1, JAK3, JAK2 | SIGMAR1 1347/4885POLB 509/4885MAPK1 73/4885 |
| US-20210155574-A1 | METHOD FOR SYNTHESIZING AMINES | PNMT, ADH1A, ADH1C | SIGMAR1 1209/4885POLB 731/4885MAPK1 2036/4885 |
| US-20250084106-A1 | PROCESS FOR PREPARING 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES AND SYNTHETIC INTERMEDIATES THEREOF | JAK1, JAK3, JAK2 | SIGMAR1 1347/4885POLB 509/4885MAPK1 73/4885 |
| US-20250066313-A1 | Methods of Synthesis of Chiral 3,5-Disubstituted Morpholine Compounds and Intermediates Useful Therein | BAD, BID, AIFM1 | SIGMAR1 2275/4885POLB 322/4885MAPK1 2490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.