SCHEMBL1006038

SCHEMBL1006038

CN1CC[C@]2(c3cccc4c3N[C@@H]3N(C)CC[C@]43[C@@]34CCN(C)[C@@H]3Nc3ccccc34)c3ccccc3N[C@H]12

nearest known ligand 0.73

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 4/20 0.36
ACHE P22303 8/20 0.36
BCHE P06276 5/20 0.36
EHMT2 Q96KQ7 5/20 0.35
SUV39H1 O43463 2/20 0.35
NSD2 O96028 1/20 0.33
EP300 Q09472 1/20 0.33
HIF1A Q16665 1/20 0.33
TXNRD1 Q16881 1/20 0.33
NSD1 Q96L73 1/20 0.33
NSD3 Q9BZ95 1/20 0.33
SIGMAR1 Q99720 1/20 0.32
CNR1 P21554 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20927487 1.00 TACR1 (0.36) TACR1ACHEBCHEEHMT2SUV39H1
SCHEMBL31672721 1.00 TACR1 (0.36) TACR1ACHEBCHEEHMT2SUV39H1
SCHEMBL29776833 1.00 TACR1 (0.36) TACR1ACHEBCHEEHMT2SUV39H1
SCHEMBL19655969 1.00 TACR1 (0.36) TACR1ACHEBCHEEHMT2SUV39H1
SCHEMBL19656075 1.00 TACR1 (0.36) TACR1ACHEBCHEEHMT2SUV39H1
SCHEMBL19657100 1.00 TACR1 (0.36) TACR1ACHEBCHEEHMT2SUV39H1
SCHEMBL30338080 1.00 TACR1 (0.36) TACR1ACHEBCHEEHMT2SUV39H1
SCHEMBL20927482 1.00 TACR1 (0.36) TACR1ACHEBCHEEHMT2SUV39H1
SCHEMBL20927481 0.99 ACHE (0.36) TACR1ACHEBCHEEHMT2SUV39H1
SCHEMBL20508875 0.99 ACHE (0.36) TACR1ACHEBCHEEHMT2SUV39H1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230355596-A1 COMPOSITIONS AND METHODS OF USING NMDAR INHIBITORS AND KINASE INHIBITORS TO TREAT LIVER CANCER VERSITECH LIMITED (CN) 2023-11-09 US claimed
EP-3560484-A1 ABUSE-DETERRENT PHARMACEUTICAL COMPOSITION G.L. Pharma GmbH (AT) 2019-10-30 EP claimed
EP-3423034-B1 ABUSE-DETERRENT PHARMACEUTICAL COMPOSITION G L PHARMA GMBH (AT) 2019-07-10 EP claimed
EP-3423034-A1 ABUSE-DETERRENT PHARMACEUTICAL COMPOSITION G.L. Pharma GmbH (AT) 2019-01-09 EP claimed
CN-109069419-A Abuse resistant drugs composition G.L.制药有限责任公司 2018-12-21 CN claimed
EP-3210596-A1 ABUSE-DETERRENT PHARMACEUTICAL COMPOSITION G.L. Pharma GmbH (AT) 2017-08-30 EP claimed
US-20260060822-A1 BIOENGINEERED SCAFFOLDS FOR VASCULAR GRAFTS AND METHODS OF USE THEREOF UNIV WAKE FOREST HEALTH SCIENCES (US) 2026-03-05 US disclosed
US-12527770-B2 Methods of managing pain using dexmedetomidine transdermal delivery devices TEIKOKU PHARMA USA, INC. (US) 2026-01-20 US disclosed
US-20250366979-A1 DEVICES AND METHODS OF MAKING AND USE THEREOF METHODIST HOSPITAL (US) 2025-12-04 US disclosed
US-20250366978-A1 DEVICES AND METHODS OF MAKING AND USE THEREOF METHODIST HOSPITAL (US) 2025-12-04 US disclosed
US-12485115-B2 Biased NMDA receptor modulators and uses thereof EDWARD Via COLLEGE OF OSTEOPATHIC MEDICINE (US) 2025-12-02 US disclosed
EP-4619763-A1 BIOMARKER PANEL FOR BRAIN SPECIFIC ABNORMAL NEUROLOGICAL CONDITIONS USING BIOFLUID SAMPLES Gryphon Bio, Inc. (US) 2025-09-24 EP disclosed
US-20250251323-A1 COLLECTION PROBE AND METHODS OF USE THEREOF BAYLOR COLLEGE OF MEDICINE 2025-08-07 US disclosed
EP-2443461-A2 BIOMARKER ASSAY OF NEUROLOGICAL CONDITION Banyan Biomarkers, Inc. (US) 2012-04-25 EP disclosed
CN-102223791-A Topical formulations for treatment of neuropathy TARAXOS INC 2011-10-19 CN disclosed
US-20110178177-A1 TOPICAL FORMULATIONS FOR TREATMENT OF NEUROPATHY TARAXOS INC. (US) 2011-07-21 US disclosed
EP-2334176-A1 TOPICAL FORMULATIONS FOR TREATMENT OF NEUROPATHY Taraxos Inc. (US) 2011-06-22 EP disclosed
WO-2011011334-A2 SYNERGISTIC BIOMARKER ASSAY OF NEUROLGICAL CONDITION USING S-100β BANYAN BIOMARKERS, INC. (US) 2011-01-27 WO disclosed
WO-2010148391-A2 BIOMARKER ASSAY OF NEUROLOGICAL CONDITION BANYAN BIOMARKERS, INC. (US) 2010-12-23 WO disclosed
WO-2010036937-A1 TOPICAL FORMULATIONS FOR TREATMENT OF NEUROPATHY TARAXOS INC. (US) 2010-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230355596-A1 COMPOSITIONS AND METHODS OF USING NMDAR INHIBITORS AND KINASE INHIBITORS TO TREAT LIVER CANCER GRIN1, GRIN3A, GRIN3B TACR1 2324/4885ACHE 1374/4885BCHE 1113/4885
US-20260060822-A1 BIOENGINEERED SCAFFOLDS FOR VASCULAR GRAFTS AND METHODS OF USE THEREOF PFKP, PBK, MYLK TACR1 4182/4885ACHE 1620/4885BCHE 804/4885
US-12527770-B2 Methods of managing pain using dexmedetomidine transdermal delivery devices OPRD1, OPRK1, OPRM1 TACR1 182/4885ACHE 660/4885BCHE 3201/4885
US-12485115-B2 Biased NMDA receptor modulators and uses thereof GRIN1, GRIN2A, GRIN3A TACR1 82/4885ACHE 681/4885BCHE 2135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.