Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | PADI1 | Q9ULC6 | 3/20 | 0.31 |
| ▸ | PADI3 | Q9ULW8 | 3/20 | 0.31 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.31 |
| ▸ | PADI2 | Q9Y2J8 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16299579 | 0.87 | NOD1 (0.32) | NOD1SIRT5 | |
| SCHEMBL14295763 | 0.85 | NOD1 (0.33) | NOD1SIRT5 | |
| SCHEMBL8261480 | 0.82 | SIRT5 (0.44) | NOD1SIRT5PADI1PADI3PADI4 | |
| SCHEMBL24824249 | 0.79 | HPGDS (0.42) | GRIA1 | |
| SCHEMBL14951121 | 0.78 | NOD1 (0.32) | NOD1 | |
| SCHEMBL14951733 | 0.76 | GNPAT (0.34) | NOD1 | |
| SCHEMBL24826060 | 0.74 | GRIA1 (0.40) | GRIA1SIRT5ALB | |
| SCHEMBL24433802 | 0.72 | GRIA1 (0.35) | GRIA1 | |
| SCHEMBL26781561 | 0.72 | TGFBR1 (0.39) | GRIA1 | |
| SCHEMBL24805405 | 0.72 | C3AR1 (0.48) | NOD1GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004270-A1 | SPIROCYCLICALLY SUBSTITUTED 1,3-PROPANE DIOXIDE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2012-01-12 | — | — | WO | disclosed |