Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | TLR2 | O60603 | 2/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.52 |
| ▸ | ECE1 | P42892 | 2/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10035700 | 0.92 | CTSK (0.55) | CTSLCTSSTLR2SIRT2SIRT1 | |
| SCHEMBL10035721 | 0.92 | CTSK (0.55) | CTSLCTSSTLR2SIRT2SIRT1 | |
| SCHEMBL17382634 | 0.88 | TLR2 (0.62) | CTSLCTSSTLR2SIRT2SIRT1 | |
| SCHEMBL29674796 | 0.87 | ECE1 (0.59) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL8230136 | 0.85 | CTSL (0.51) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL8230194 | 0.84 | TGM2 (0.58) | CTSLCTSS | |
| SCHEMBL8233297 | 0.84 | SYK (0.52) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL29576990 | 0.84 | ECE1 (0.63) | TLR2SIRT2SIRT1SIRT3ECE1 | |
| SCHEMBL10920444 | 0.84 | TLR2 (0.59) | CTSLCTSSTLR2SIRT2SIRT1 | |
| SCHEMBL25879987 | 0.82 | ALDH1A1 (0.57) | CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119653-B2 | Belactosin derivatives as therapeutic agents/biological probes and their synthesis | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2012-02-21 | — | — | US | disclosed |