Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 15/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 11/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 6/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10035711 | 0.93 | CTSK (0.49) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL8230194 | 0.92 | TGM2 (0.58) | CTSLCTSSTGM2 | |
| SCHEMBL8233297 | 0.88 | SYK (0.52) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL10067246 | 0.85 | CTSL (0.53) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL10035707 | 0.84 | TGM2 (0.59) | TGM2 | |
| SCHEMBL10035709 | 0.80 | SYK (0.54) | CTSLCTSS | |
| SCHEMBL8232317 | 0.80 | PSMB5 (0.57) | CTSLCTSS | |
| SCHEMBL8232318 | 0.80 | PSMB5 (0.57) | CTSLCTSS | |
| SCHEMBL25879987 | 0.78 | ALDH1A1 (0.57) | CTSLCTSS | |
| SCHEMBL16907368 | 0.77 | CTSL (0.60) | CTSLCTSSSIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119653-B2 | Belactosin derivatives as therapeutic agents/biological probes and their synthesis | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2012-02-21 | — | — | US | disclosed |
| US-20090042922-A1 | NOVEL BELACTOSIN DERIVATIVES AS THERAPEUTIC AGENTS/BIOLOGICAL PROBES AND THEIR SYNTHESIS | NATIONAL SCIENCE FOUNDATION | 2009-02-12 | — | — | US | disclosed |
| WO-2008006113-A2 | NOVEL BELACTOSIN DERIVATIVES AS THERAPEUTIC AGENTS/BIOLOGICAL PROBES AND THEIR SYNTHESIS | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042922-A1 | NOVEL BELACTOSIN DERIVATIVES AS THERAPEUTIC AGENTS/BIOLOGICAL PROBES AND THEIR SYNTHESIS | PSMB1, PSMB10, PBK | CTSL 836/4885CTSS 760/4885SIRT2 4029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.