SCHEMBL10067409

SCHEMBL10067409

C=C(NC)C1CC2C(=C)N(c3ccc(Oc4ccc(-c5ccc(Oc6ccc(C)cc6)cc5)cc4)cc3)C(=O)C2CC1C=O

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
MMP13 P45452 1/20 0.31
FFAR1 O14842 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10067765 0.76 LMNA (0.41) LMNAFFAR1MEN1KMT2A
SCHEMBL13634488 0.75 MMP13 (0.36) LMNAMMP13FFAR1MEN1KMT2A
SCHEMBL13899154 0.74 LMNA (0.34) LMNAFFAR1
SCHEMBL13634454 0.71 ALDH1A1 (0.41) LMNAMEN1KMT2A
SCHEMBL13624488 0.69 LMNA (0.46) LMNAMEN1KMT2A
SCHEMBL9911156 0.65 LMNA (0.49) LMNAMEN1KMT2A
SCHEMBL13634424 0.62 ALDH1A1 (0.42) LMNAMEN1KMT2A
SCHEMBL10098933 0.61 LMNA (0.51) LMNAKMT2A
SCHEMBL13473842 0.61 ALDH1A1 (0.47) LMNAMMP13MEN1KMT2A
SCHEMBL13855427 0.60 TP53 (0.46) LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2039716-B1 POLYIMIDE RESIN MITSUBISHI GAS CHEMICAL CO (JP) 2012-02-22 EP disclosed
EP-2039716-A1 POLYIMIDE RESIN Mitsubishi Gas Chemical Company, Inc. (JP) 2009-03-25 EP disclosed