SCHEMBL13899154

SCHEMBL13899154

C=C(C1CC2C(=C)N(c3ccc(Oc4ccc(-c5ccc(Oc6ccc(C)cc6)cc5)cc4)cc3)C(=O)C2CC1CO)N(C)C

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
MGLL Q99685 1/20 0.31
FFAR1 O14842 1/20 0.31
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
HPGD P15428 1/20 0.30
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10067765 0.76 LMNA (0.41) LMNAFFAR1ALDH1A1
SCHEMBL10067409 0.74 LMNA (0.34) LMNAFFAR1
SCHEMBL13624488 0.69 LMNA (0.46) LMNAALDH1A1
SCHEMBL9911156 0.65 LMNA (0.49) LMNAMGLLALDH1A1GAAHPGD
SCHEMBL13472599 0.61 LMNA (0.43) LMNAALDH1A1
SCHEMBL13855427 0.60 TP53 (0.46) LMNAMGLLALDH1A1GAAHPGD
SCHEMBL14342131 0.59 LMNA (0.46) LMNAALDH1A1GAA
SCHEMBL13855428 0.58 LMNA (0.46) LMNAFFAR1ALDH1A1GAAHPGD
SCHEMBL16201615 0.58 LMNA (0.40) LMNAALDH1A1GAA
SCHEMBL12330617 0.58 KDM1A (0.46) ALDH1A1GAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2039716-A1 POLYIMIDE RESIN Mitsubishi Gas Chemical Company, Inc. (JP) 2009-03-25 EP disclosed