SCHEMBL10067765

SCHEMBL10067765

C=C1C2CC3C(=C)N(c4ccc(Oc5ccc(-c6ccc(Oc7ccc(C)cc7)cc6)cc5)cc4)C(=O)C3CC2C(=O)N1C

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.35
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
POLB P06746 1/20 0.34
ACHE P22303 1/20 0.34
MAPT P10636 2/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33
F2 P00734 1/20 0.33
ELANE P08246 1/20 0.33
CTSG P08311 1/20 0.33
CMA1 P23946 1/20 0.33
CTRC Q99895 1/20 0.33
APOBEC3G Q9HC16 1/20 0.32
FFAR1 O14842 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13624488 0.88 LMNA (0.46) LMNASMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL9911156 0.84 LMNA (0.49) LMNASMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL14342131 0.77 LMNA (0.46) LMNASMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL13472599 0.76 LMNA (0.43) LMNASMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL13899154 0.76 LMNA (0.34) LMNAALDH1A1FFAR1
SCHEMBL10067409 0.76 LMNA (0.34) LMNAMEN1KMT2AFFAR1
SCHEMBL13472598 0.75 LMNA (0.56) LMNAALDH1A1POLBACHEMAPT
SCHEMBL13855427 0.73 TP53 (0.46) LMNASMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL16201615 0.73 LMNA (0.40) LMNASMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL13855428 0.71 LMNA (0.46) LMNASMN1; SMN2ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2039716-B1 POLYIMIDE RESIN MITSUBISHI GAS CHEMICAL CO (JP) 2012-02-22 EP disclosed
EP-2039716-A1 POLYIMIDE RESIN Mitsubishi Gas Chemical Company, Inc. (JP) 2009-03-25 EP disclosed