Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11466073 | 0.98 | FFAR1 (0.56) | FFAR1ALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL11038206 | 0.85 | ALDH1A1 (0.55) | FFAR1ALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL13768114 | 0.84 | POLB (0.50) | FFAR1ALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL25121838 | 0.82 | MAPT (0.43) | FFAR1ALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL15075268 | 0.82 | MAPT (0.43) | FFAR1ALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL8068242 | 0.82 | CA2 (0.53) | CA2LMNA | |
| SCHEMBL5458094 | 0.82 | ALDH1A1 (0.61) | FFAR1ALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL13611310 | 0.82 | FFAR1 (0.59) | FFAR1ALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL9781961 | 0.81 | FFAR1 (0.54) | FFAR1ALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| Oxalic Acid SCHEMBL9716123 | 0.81 | LMNA (0.55) | FFAR1ALDH1A1HPGDSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077711-A1 | Novel Ligands and Libraries of Ligands | SUNESIS PHARMACEUTICALS, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| US-8138361-B2 | C-10 carbamates of taxanes | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-03-20 | — | — | US | disclosed |
| US-20090306014-A1 | C-10 CARBAMATES OF TAXANES | ACIDOPHIL LLC (US) | 2009-12-10 | — | — | US | disclosed |
| US-3957850-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | BOUCHARA EMILE | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306014-A1 | C-10 CARBAMATES OF TAXANES | CASP10, S100A10, ATXN10 | FFAR1 4224/4885ALDH1A1 1408/4885HSD17B10 781/4885 |
| US-20120077711-A1 | Novel Ligands and Libraries of Ligands | LSS, ABCG2, SELL | FFAR1 302/4885ALDH1A1 533/4885HSD17B10 2891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.