Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 8/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069590 | 0.90 | ALDH1A1 (0.39) | ELANESMN1; SMN2ALDH1A1 | |
| SCHEMBL10069601 | 0.87 | ALDH1A1 (0.36) | MEN1KMT2AKDM4EELANEALDH1A1 | |
| SCHEMBL10069594 | 0.87 | MAPT (0.38) | KDM4EARELANETP53ALDH1A1 | |
| SCHEMBL10069600 | 0.86 | AR (0.42) | MEN1HTTKMT2AKDM4ERXFP1 | |
| SCHEMBL10069591 | 0.84 | ESR1 (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL10069595 | 0.82 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL10069611 | 0.82 | L3MBTL1 (0.36) | KDM4EARSMN1; SMN2ALDH1A1 | |
| SCHEMBL10069619 | 0.81 | KDM5B (0.34) | ARTP53 | |
| SCHEMBL10069616 | 0.78 | ALDH1A1 (0.36) | MEN1KMT2AKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL10069596 | 0.77 | MAPT (0.36) | MEN1HTTKMT2ARAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047993-A2 | N-HYDROXYPYRIMIDINE-2,4-DIONES AS INHIBITORS OF HIV AND HCV | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2012-04-12 | — | — | WO | disclosed |