SCHEMBL10070041

SCHEMBL10070041

CCCC1OC(=O)CCCC1OC(=O)C1CC2C=CC1C2

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.35
ALDH1A1 P00352 7/20 0.33
POLB P06746 3/20 0.33
APEX1 P27695 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
ESR2 Q92731 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 2/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
HMGCR P04035 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9909395 0.75 PRKCA (0.40) PRKCAPOLBRECQLTDP1RAB9A
SCHEMBL11982284 0.73 PRKCA (0.41) PRKCA
SCHEMBL22789979 0.69 LMNA (0.41) ALDH1A1POLBAPEX1RECQLBLM
SCHEMBL75458 0.69 LMNA (0.41) ALDH1A1POLBAPEX1RECQLBLM
SCHEMBL12514940 0.69 LMNA (0.42) ALDH1A1POLBAPEX1RECQLBLM
SCHEMBL3872267 0.68 POLB (0.42) ALDH1A1POLBAPEX1RECQLBLM
SCHEMBL13706387 0.67 PRKCA (0.51) PRKCA
SCHEMBL13382568 0.67 LMNA (0.50) ALDH1A1POLBAPEX1RECQLBLM
SCHEMBL3873471 0.67 KDM4E (0.36) ALDH1A1POLBAPEX1RECQLBLM
SCHEMBL3871321 0.66 KDM4E (0.40) ALDH1A1POLBAPEX1RECQLBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120009527-A1 PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-01-12 US disclosed