Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10681711 | 0.82 | ALDH1A1 (0.50) | PDK1ALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL27783019 | 0.75 | PDK1 (0.43) | PDK1ALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL27761231 | 0.75 | PDK1 (0.43) | PDK1ALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL21723550 | 0.71 | L3MBTL1 (0.47) | MEN1KMT2AACP1 | |
| SCHEMBL27965263 | 0.70 | CFD (0.52) | ALDH1A1SMN1; SMN2MEN1MAPTHPGD | |
| SCHEMBL27964937 | 0.70 | CFD (0.63) | ALDH1A1SMN1; SMN2MEN1MAPTHPGD | |
| SCHEMBL10958189 | 0.69 | MEN1 (0.67) | ALDH1A1SMN1; SMN2MEN1MAPTHPGD | |
| SCHEMBL28131774 | 0.69 | S1PR2 (0.43) | ALDH1A1SMN1; SMN2MEN1MAPTHTT | |
| SCHEMBL27809773 | 0.68 | CA2 (0.43) | MAPTHPGDKDM4EGAA | |
| SCHEMBL27617893 | 0.67 | MEN1 (0.63) | PDK1ALDH1A1SMN1; SMN2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020221-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | disclosed |