Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10079674 | 0.76 | KDM4E (0.48) | MEN1KMT2APLAURAB9ASMN1; SMN2 | |
| SCHEMBL10079637 | 0.71 | KDM4E (0.50) | MEN1KMT2APLAURAB9ASMN1; SMN2 | |
| SCHEMBL11224213 | 0.67 | LMNA (0.35) | PKMRAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13660347 | 0.64 | MEN1 (0.45) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8311758 | 0.63 | ALDH1A1 (0.38) | PKMMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL4841594 | 0.63 | MAPT (0.49) | MEN1KMT2APLAURAB9ANPC1 | |
| SCHEMBL10810009 | 0.63 | ZDHHC20 (0.45) | RAB9ASMN1; SMN2LMNATP53MAPK1 | |
| SCHEMBL1872509 | 0.63 | LMNA (0.45) | RAB9ASMN1; SMN2ALDH1A1LMNAMAPK1 | |
| SCHEMBL10971819 | 0.63 | GAA (0.47) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4841582 | 0.62 | MAPT (0.48) | MEN1KMT2APLAURAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020221-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | disclosed |