Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RHOC | P08134 | 1/20 | 0.35 |
| ▸ | RHOA | P61586 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8527274 | 0.65 | KMT2A (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2APKM | |
| SCHEMBL38654908 | 0.65 | SMN1; SMN2 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL6382771 | 0.64 | MTNR1A (0.65) | SMN1; SMN2POLBPKMNPC1RAB9A | |
| SCHEMBL6565977 | 0.63 | TSHR (0.58) | ALDH1A1RAB9ACA12CA2CA4 | |
| SCHEMBL10070607 | 0.63 | PKM (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2APKM | |
| SCHEMBL23568434 | 0.63 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KMT2APOLBNPC1 | |
| SCHEMBL28696934 | 0.62 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL19399650 | 0.62 | CA3 (0.56) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL11570722 | 0.62 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL27202277 | 0.62 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964853-A1 | 4-AMINOALKOXY-1,3-DIHYDROBENZOIMIDAZOL-2-ONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE AUTORECEPTOR (D2) AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-12-22 | — | — | EP | disclosed |
| WO-1998035946-A1 | 4-AMINOALKOXY-1,3-DIHYDROBENZOIMIDAZOL-2-ONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE AUTORECEPTOR (D2) AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-08-20 | — | — | WO | disclosed |