SCHEMBL13660347

SCHEMBL13660347

O=C(NCCOCCOCCNC(=O)C(Cl)(Cl)Cl)C(Cl)(Cl)Cl

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
SMN1; SMN2 Q16637 3/20 0.41
LMNA P02545 3/20 0.40
PYGL P06737 2/20 0.33
ALDH1A1 P00352 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
POLB P06746 1/20 0.33
CA2 P00918 4/20 0.32
RAB9A P51151 1/20 0.32
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA4 P22748 2/20 0.31
CA9 Q16790 2/20 0.31
CA14 Q9ULX7 2/20 0.31
EPHX2 P34913 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13660343 0.87 ALDH1A1 (0.45) MEN1KMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL14008193 0.83 THRB (0.53) MEN1KMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL10971819 0.80 GAA (0.47) MEN1KMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL1457136 0.78 LMNA (0.38) MEN1KMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL13432085 0.77 SMN1; SMN2 (0.46) MEN1KMT2ASMN1; SMN2LMNAPYGL
SCHEMBL5066367 0.77 MEN1 (0.50) MEN1KMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL14008176 0.77 EPHX1 (0.49) SMN1; SMN2ALDH1A1GAA
SCHEMBL14008189 0.75 THRB (0.44) MEN1KMT2ALMNAALDH1A1L3MBTL1
SCHEMBL22821424 0.74 MEN1 (0.47) MEN1KMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL38654908 0.74 SMN1; SMN2 (0.62) MEN1KMT2ASMN1; SMN2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090263744-A1 ETHYLENICALLY UNSATURATED COMPOUND, LIGHT SENSITIVE COMPOSITION, LIGHT SENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL AND PRINTING PROCESS EMPLOYING THE SAME KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-10-22 US disclosed
US-20090263744-A1 ETHYLENICALLY UNSATURATED COMPOUND, LIGHT SENSITIVE COMPOSITION, LIGHT SENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL AND PRINTING PROCESS EMPLOYING THE SAME KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-10-22 US disclosed
US-20090042134-A1 Photosensitive composition, photosensitive planographic printing plate material, and image forming method of photosensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC INC. (JP) 2009-02-12 US disclosed
US-20090042134-A1 Photosensitive composition, photosensitive planographic printing plate material, and image forming method of photosensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC INC. (JP) 2009-02-12 US disclosed
US-20080274425-A1 Multilayeer; aluminum support with fluoroalkyl acrylic group containing polymer; alkali soluble resin and an acid generator KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-11-06 US disclosed
US-20080274425-A1 Multilayeer; aluminum support with fluoroalkyl acrylic group containing polymer; alkali soluble resin and an acid generator KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-11-06 US disclosed
US-20080182202-A1 Planographic printing plate material and resin used therein KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-31 US disclosed
US-20080182202-A1 Planographic printing plate material and resin used therein KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-31 US disclosed
US-20080160445-A1 Planographic printing plate material, and method of preparing planographic printing plate employing the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-03 US disclosed
US-20080160445-A1 Planographic printing plate material, and method of preparing planographic printing plate employing the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-03 US disclosed
US-7285375-B2 Photosensitive composition, photosensitive lithography plate and method for producing lithography plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-10-23 US disclosed
US-7285375-B2 Photosensitive composition, photosensitive lithography plate and method for producing lithography plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-10-23 US disclosed
US-7273692-B2 Planographic printing plate material and planographic printing plate preparing process KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-09-25 US disclosed
US-7273692-B2 Planographic printing plate material and planographic printing plate preparing process KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-09-25 US disclosed
US-7172851-B2 Light sensitive composition, planographic printing plate material, and image formation method KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-02-06 US disclosed
US-7172851-B2 Light sensitive composition, planographic printing plate material, and image formation method KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-02-06 US disclosed
US-20070020555-A1 Photosensitive composition, photosensitive lithography plate and method for producing lithography plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-25 US disclosed
US-20070020555-A1 Photosensitive composition, photosensitive lithography plate and method for producing lithography plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-25 US disclosed
US-20070015086-A1 Photosensitive composition, photosensitive planographic printing plate material, and image forming method of photosensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2007-01-18 US disclosed
US-20070015086-A1 Photosensitive composition, photosensitive planographic printing plate material, and image forming method of photosensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2007-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090263744-A1 ETHYLENICALLY UNSATURATED COMPOUND, LIGHT SENSITIVE COMPOSITION, LIGHT SENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL AND PRINTING PROCESS EMPLOYING THE SAME ELOVL1, ELOVL6, ELOVL3 MEN1 4583/4885KMT2A 2963/4885SMN1; SMN2 4662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.