Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10072089 | 0.86 | NOTUM (0.32) | PDE2AMAPT | |
| SCHEMBL12565130 | 0.81 | MEN1 (0.33) | — | |
| SCHEMBL837116 | 0.80 | PDE2A (0.41) | PDE2AALDH1A1MAPT | |
| SCHEMBL13268220 | 0.77 | CFTR (0.45) | ALDH1A1MAPT | |
| SCHEMBL13080948 | 0.77 | LPL (0.33) | — | |
| SCHEMBL14792949 | 0.75 | TSHR (0.34) | — | |
| SCHEMBL13118388 | 0.73 | KIF11 (0.34) | ALDH1A1 | |
| SCHEMBL12920534 | 0.71 | PTGDR2 (0.36) | MAPT | |
| SCHEMBL12565133 | 0.70 | PPARD (0.44) | ALDH1A1MAPT | |
| SCHEMBL22366955 | 0.70 | LIPE (0.34) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143068-B2 | Oxidation resistant indicator molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2012-03-27 | — | — | US | disclosed |
| US-20110081727-A1 | Oxidation Resistant Indicator Molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110081727-A1 | Oxidation Resistant Indicator Molecules | AOX1, GPX4, SQOR | PDE2A 4157/4885ALDH1A1 129/4885MAPT 4290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.