SCHEMBL10072222

SCHEMBL10072222

CCN(CC)c1ccc(C(CC=C(c2ccc(CCOC(=O)OC)cc2)c2ccc(CCOC(=O)OC)cc2)c2ccc(N(CC)CC)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 7/20 0.42
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
ESRRG P62508 4/20 0.41
ESRRB O95718 1/20 0.41
AOC3 Q16853 1/20 0.39
MAPT P10636 2/20 0.37
NPY1R P25929 1/20 0.35
NPY2R P49146 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
MCL1 Q07820 1/20 0.35
NOX1 Q9Y5S8 1/20 0.35
HSD11B1 P28845 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL279503 0.85 ESRRG (0.46) CNR2ALDH1A1TSHRESRRGESRRB
SCHEMBL9608958 0.81 ESRRG (0.43) CNR2ALDH1A1TSHRESRRGESRRB
SCHEMBL10072221 0.78 ALDH1A1 (0.40) CNR2ALDH1A1TSHRMAPTNPY1R
SCHEMBL14173008 0.75 CNR2 (0.48) CNR2ALDH1A1TSHRESRRGMAPT
SCHEMBL13950799 0.71 RAB9A (0.45) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL27735436 0.69 ESR1 (0.64) CNR2ALDH1A1TSHRESRRGMAPT
SCHEMBL9607524 0.68 MAPT (0.39) ALDH1A1MAPTMEN1KMT2AGAA
SCHEMBL3752742 0.68 THRB (0.48) CNR2ALDH1A1TSHRESRRGESRRB
SCHEMBL2021869 0.66 HCAR2 (0.54) ALDH1A1TSHR
SCHEMBL14100027 0.66 ALDH1A1 (0.50) CNR2ALDH1A1TSHRESRRGMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110328-B2 Conductive support with photosensitive layer containing curable resin, fluorinated surfactants and charge transfer compound FUJI XEROX CO., LTD. (JP) 2012-02-07 US disclosed
US-8110328-B2 Conductive support with photosensitive layer containing curable resin, fluorinated surfactants and charge transfer compound FUJI XEROX CO., LTD. (JP) 2012-02-07 US disclosed
US-20080261135-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2008-10-23 US disclosed
US-20080261135-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2008-10-23 US disclosed