SCHEMBL10072221

SCHEMBL10072221

CCOC(=O)Oc1ccc(C(CC=C(c2ccc(N(CC)CC)cc2)c2ccc(N(CC)CC)cc2)c2ccc(OC(=O)OCC)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
TSHR P16473 2/20 0.40
CNR2 P34972 6/20 0.39
NPY1R P25929 1/20 0.36
NPY2R P49146 1/20 0.36
HSD11B1 P28845 1/20 0.36
KMT2A Q03164 6/20 0.36
MAPT P10636 5/20 0.36
MEN1 O00255 5/20 0.36
MAPK1 P28482 4/20 0.36
POLB P06746 4/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
USP2 O75604 1/20 0.36
RECQL P46063 1/20 0.36
TLR9 Q9NR96 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
HTT P42858 1/20 0.35
THRB P10828 2/20 0.35
PKM P14618 2/20 0.35
HPGD P15428 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL279048 0.83 MAPT (0.40) ALDH1A1TSHRNPY1RNPY2RHSD11B1
SCHEMBL10072222 0.78 CNR2 (0.42) ALDH1A1TSHRCNR2NPY1RNPY2R
SCHEMBL14173008 0.77 CNR2 (0.48) ALDH1A1TSHRCNR2HSD11B1KMT2A
SCHEMBL3438583 0.70 PRSS1 (0.57) ALDH1A1TSHRKMT2AMAPTMEN1
SCHEMBL3789020 0.69 HSD17B10 (0.53) ALDH1A1TSHRKMT2AMAPTMAPK1
SCHEMBL9607523 0.69 LMNA (0.44) KMT2AMEN1USP2RECQLGAA
SCHEMBL279037 0.68 KMT2A (0.51) ALDH1A1KMT2AMAPTMEN1L3MBTL1
SCHEMBL6451238 0.68 ALDH1A1 (0.55) ALDH1A1TSHRKMT2AMAPTMEN1
SCHEMBL862441 0.68 KMT2A (0.46) ALDH1A1TSHRKMT2AMAPTMEN1
SCHEMBL8983166 0.68 SMN1; SMN2 (0.51) KMT2AMAPTMEN1L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110328-B2 Conductive support with photosensitive layer containing curable resin, fluorinated surfactants and charge transfer compound FUJI XEROX CO., LTD. (JP) 2012-02-07 US disclosed
US-8110328-B2 Conductive support with photosensitive layer containing curable resin, fluorinated surfactants and charge transfer compound FUJI XEROX CO., LTD. (JP) 2012-02-07 US disclosed
US-20080261135-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2008-10-23 US disclosed
US-20080261135-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2008-10-23 US disclosed