SCHEMBL9608958

SCHEMBL9608958

CCOC(=O)OCCc1ccc(C(=CC=C(c2ccc(N(CC)CC)cc2)c2ccc(N(CC)CC)cc2)c2ccc(CCOC(=O)OC)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESRRG P62508 4/20 0.43
ESRRB O95718 1/20 0.43
NPY1R P25929 1/20 0.42
NPY2R P49146 1/20 0.42
AOC3 Q16853 2/20 0.41
MAPT P10636 5/20 0.39
ALDH1A1 P00352 4/20 0.39
TSHR P16473 2/20 0.39
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
POLB P06746 2/20 0.37
GAA P10253 1/20 0.37
MCL1 Q07820 1/20 0.37
NOX1 Q9Y5S8 1/20 0.37
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37
HPGD P15428 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HSD17B10 Q99714 1/20 0.36
NPC1 O15118 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL279503 0.95 ESRRG (0.46) ESRRGESRRBNPY1RNPY2RAOC3
SCHEMBL9607524 0.87 MAPT (0.39) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL13950799 0.81 RAB9A (0.45) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL10072222 0.81 CNR2 (0.42) ESRRGESRRBNPY1RNPY2RAOC3
SCHEMBL279048 0.77 MAPT (0.40) NPY1RNPY2RMAPTALDH1A1TSHR
SCHEMBL14283581 0.72 ALDH1A1 (0.52) ESRRGMAPTALDH1A1TSHRMEN1
SCHEMBL13681245 0.72 ESRRG (0.42) ESRRGESRRBAOC3MAPTALDH1A1
SCHEMBL279192 0.70 MET (0.43) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL3752742 0.70 THRB (0.48) ESRRGESRRBAOC3MAPTALDH1A1
SCHEMBL13483588 0.70 KMT2A (0.44) MAPTALDH1A1KMT2AHPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed