SCHEMBL9607524

SCHEMBL9607524

CCOC(=O)OCCc1ccc(C(=CC=C(c2ccc(C)cc2)c2ccc(C)cc2)c2ccc(CCOC(=O)OC)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PPARG P37231 1/20 0.38
PPARD Q03181 1/20 0.38
PPARA Q07869 1/20 0.38
LMNA P02545 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KMT2A Q03164 4/20 0.37
MEN1 O00255 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
ALDH1A1 P00352 1/20 0.37
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36
TBXA2R P21731 1/20 0.36
TBXAS1 P24557 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
DHODH Q02127 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9608958 0.87 ESRRG (0.43) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL13950799 0.87 RAB9A (0.45) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL13483588 0.83 KMT2A (0.44) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL279503 0.81 ESRRG (0.46) MAPTNPC1RAB9ASMN1; SMN2KMT2A
P-Xylene SCHEMBL11129735 0.75 ALDH1A1 (0.59) MAPTRAB9ASMN1; SMN2LMNAL3MBTL1
SCHEMBL279192 0.74 MET (0.43) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL9607523 0.74 LMNA (0.44) SMN1; SMN2PPARGPPARDPPARALMNA
SCHEMBL1891083 0.72 ALDH1A1 (0.65) MAPTLMNAALDH1A1GAA
SCHEMBL12317152 0.71 CHRM2 (0.43) PPARGPPARAL3MBTL1KMT2AMEN1
SCHEMBL2023807 0.71 HCAR2 (0.53) MAPTNPC1RAB9ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed