Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13348380 | 0.90 | TSHR (0.34) | TSHRHPGD | |
| SCHEMBL13435134 | 0.88 | TSHR (0.38) | TLR4TSHRHPGD | |
| SCHEMBL10074039 | 0.81 | TLR4 (0.39) | TLR4CYP2C9 | |
| SCHEMBL23493922 | 0.79 | ALDH1A1 (0.38) | TSHRHPGD | |
| SCHEMBL27993788 | 0.77 | TSHR (0.33) | TSHRTHRATHRBHPGDCYP2C9 | |
| SCHEMBL15480715 | 0.76 | TSHR (0.50) | TLR4TSHRTHRATHRBHPGD | |
| SCHEMBL74873 | 0.76 | TLR4 (0.37) | TLR4TSHRTHRATHRBHPGD | |
| SCHEMBL12154173 | 0.76 | TSHR (0.42) | TLR4TSHRTHRATHRBHPGD | |
| SCHEMBL17147338 | 0.75 | CTSK (0.35) | TLR4 | |
| SCHEMBL565179 | 0.74 | TSHR (0.46) | TSHRTHRATHRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2087067-B1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | MERCK PATENT GMBH (DE) | 2012-06-27 | — | — | EP | disclosed |
| US-20100103366-A1 | Cyclohexylene Reactive Mesogens and Their Applications | MERCK PATENT GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
| WO-2008061606-A1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | MERCK PATENT GMBH (DE) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100103366-A1 | Cyclohexylene Reactive Mesogens and Their Applications | CUTA, MC1R, CTSG | TLR4 1372/4885TSHR 3118/4885THRA 3899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.