Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 6/20 | 0.70 |
| ▸ | TUBB | P07437 | 6/20 | 0.70 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.70 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.70 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.70 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.70 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.70 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.70 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.70 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.70 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.70 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.70 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.70 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.70 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL682248 | 1.00 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL682432 | 0.93 | TUBB4A (0.81) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL681552 | 0.91 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10073422 | 0.91 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10073425 | 0.87 | TUBB4A (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14877931 | 0.86 | TUBB4A (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL682471 | 0.85 | TUBB4A (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14713710 | 0.84 | TUBB4A (0.81) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL681526 | 0.84 | TUBB4A (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10073426 | 0.83 | CYP3A4 (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841317-B2 | Noscapine and analogs and methods related thereto | EMORY UNIVERSITY (US) | 2014-09-23 | — | — | US | disclosed |
| US-20130045203-A1 | Uses of Noscapine and Derivatives in Subjects Diagnosed with FAP | EMORY UNIVERSITY (US) | 2013-02-21 | — | — | US | disclosed |
| US-20120053199-A1 | NOSCAPINE AND ANALOGS AND METHODS RELATED THERETO | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053199-A1 | NOSCAPINE AND ANALOGS AND METHODS RELATED THERETO | NOS2, NOS1, NOS3 | TUBB4A 3007/4885TUBB 3641/4885TUBA3C 4036/4885 |
| US-20130045203-A1 | Uses of Noscapine and Derivatives in Subjects Diagnosed with FAP | APC, FAP, NTPCR | TUBB4A 2727/4885TUBB 3171/4885TUBA3C 4007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.