Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 3/20 | 0.32 |
| ▸ | HRH1 | P35367 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12844635 | 0.89 | CYP19A1 (0.41) | CYP19A1TP53ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL13510862 | 0.88 | SMN1; SMN2 (0.35) | TP53ALDH1A1TSHRSMN1; SMN2HRH1 | |
| SCHEMBL13730325 | 0.85 | SMN1; SMN2 (0.33) | TP53ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL12863838 | 0.85 | TP53 (0.47) | CYP19A1TP53ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL464417 | 0.84 | ALDH1A1 (0.38) | TP53ALDH1A1TSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL12650302 | 0.83 | ALDH1A1 (0.32) | CYP19A1ALDH1A1L3MBTL1 | |
| SCHEMBL12863834 | 0.82 | ALDH1A1 (0.46) | TP53ALDH1A1TSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL13496820 | 0.80 | CA1 (0.39) | CYP19A1TDP1CA1 | |
| SCHEMBL9571740 | 0.79 | SMN1; SMN2 (0.34) | TP53ALDH1A1TSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL12181288 | 0.77 | CHRM1 (0.33) | TP53ALDH1A1TSHRSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065358-A1 | BIODEGRADABLE POLY(BETA-AMINO ESTERS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-03-15 | — | — | US | disclosed |