Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14472607 | 0.86 | — | — | |
| SCHEMBL12181288 | 0.84 | CHRM1 (0.33) | ALDH1A1L3MBTL1 | |
| SCHEMBL10074652 | 0.83 | CYP19A1 (0.35) | ALDH1A1L3MBTL1CYP19A1 | |
| SCHEMBL12844635 | 0.81 | CYP19A1 (0.41) | ALDH1A1L3MBTL1CYP19A1 | |
| SCHEMBL12863838 | 0.77 | TP53 (0.47) | ALDH1A1L3MBTL1CYP19A1 | |
| SCHEMBL13730333 | 0.76 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL14286498 | 0.75 | APEX1 (0.34) | — | |
| SCHEMBL12009951 | 0.75 | ARG1 (0.31) | — | |
| SCHEMBL12863834 | 0.74 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1 | |
| SCHEMBL19102455 | 0.74 | SMN1; SMN2 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943179-B2 | Drug delivery particle; useful in genetic vaccination; eg poly(beta-amino esters) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-05-17 | — | — | US | disclosed |