Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 2/20 | 0.31 |
| ▸ | ARG2 | P78540 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12009951 | 0.90 | ARG1 (0.31) | SMN1; SMN2LTA4HARG1ARG2 | |
| SCHEMBL13510862 | 0.88 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1TSHRARG1ARG2 | |
| SCHEMBL10074652 | 0.85 | CYP19A1 (0.35) | SMN1; SMN2ALDH1A1TSHRTP53 | |
| SCHEMBL15314276 | 0.82 | SMN1; SMN2 (0.35) | SMN1; SMN2LTA4HARG1ARG2HTT | |
| SCHEMBL464417 | 0.80 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1TSHRARG1ARG2 | |
| SCHEMBL19036251 | 0.79 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1TSHRKCNH2CACNA1I | |
| SCHEMBL12181288 | 0.79 | CHRM1 (0.33) | SMN1; SMN2ALDH1A1TSHRARG1ARG2 | |
| SCHEMBL421373 | 0.79 | ALDH1A1 (0.40) | SMN1; SMN2LTA4HALDH1A1TSHRCHRM4 | |
| SCHEMBL13510873 | 0.78 | SMN1; SMN2 (0.34) | SMN1; SMN2ALDH1A1TSHRARG1ARG2 | |
| SCHEMBL14472771 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097349-A1 | THERAPEUTIC COMPOSITIONS | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2009-08-06 | — | — | WO | disclosed |