Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.30 |
| ▸ | ARG2 | P78540 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10074652 | 0.84 | CYP19A1 (0.35) | ALDH1A1TSHRSMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL13510862 | 0.82 | SMN1; SMN2 (0.35) | ALDH1A1TSHRSMN1; SMN2TP53ARG1 | |
| SCHEMBL13730325 | 0.80 | SMN1; SMN2 (0.33) | ALDH1A1TSHRSMN1; SMN2TP53ARG1 | |
| SCHEMBL12863834 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TSHRSMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL12844635 | 0.74 | CYP19A1 (0.41) | ALDH1A1TSHRSMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL12181288 | 0.73 | CHRM1 (0.33) | ALDH1A1TSHRSMN1; SMN2TP53ARG1 | |
| SCHEMBL19036251 | 0.73 | SMN1; SMN2 (0.40) | ALDH1A1TSHRSMN1; SMN2TP53 | |
| SCHEMBL13510873 | 0.73 | SMN1; SMN2 (0.34) | ALDH1A1TSHRSMN1; SMN2TP53ARG1 | |
| SCHEMBL12009951 | 0.71 | ARG1 (0.31) | SMN1; SMN2ARG1ARG2 | |
| SCHEMBL12863838 | 0.71 | TP53 (0.47) | ALDH1A1TSHRSMN1; SMN2TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065358-A1 | BIODEGRADABLE POLY(BETA-AMINO ESTERS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-03-15 | — | — | US | disclosed |