Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12863838 | 0.95 | TP53 (0.47) | CYP19A1TP53ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL12863834 | 0.92 | ALDH1A1 (0.46) | TP53ALDH1A1TSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL10074652 | 0.89 | CYP19A1 (0.35) | CYP19A1TP53ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL12863854 | 0.85 | PAOX (0.45) | CYP19A1TP53ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL673537 | 0.82 | ALDH1A1 (0.44) | TP53ALDH1A1TSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL12863835 | 0.82 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2L3MBTL1HRH2HRH1 | |
| SCHEMBL12650302 | 0.81 | ALDH1A1 (0.32) | CYP19A1ALDH1A1L3MBTL1 | |
| SCHEMBL333015 | 0.80 | ADRA2A (0.50) | CYP19A1ALDH1A1CA12CA1CA2 | |
| SCHEMBL419258 | 0.79 | ALDH1A1 (0.46) | TP53ALDH1A1TSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL674334 | 0.79 | ALDH1A1 (0.46) | TP53ALDH1A1TSHRSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557231-B2 | Biodegradable poly(beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-10-15 | — | — | US | disclosed |
| US-20110059172-A1 | THERAPEUTIC COMPOSITIONS | TZIANABOS ARTHUR | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059172-A1 | THERAPEUTIC COMPOSITIONS | PHOSPHO1, ACP1, TUBB3 | CYP19A1 4495/4885TP53 139/4885ALDH1A1 1769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.