Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684744 | 0.94 | DHODH (0.32) | DHODHNTRK1ALDH1A1CHIAGRIN1 | |
| SCHEMBL687025 | 0.93 | DHODH (0.32) | DHODHNTRK1 | |
| SCHEMBL10083275 | 0.92 | SLC2A1 (0.34) | DHODH | |
| SCHEMBL687026 | 0.92 | DHODH (0.32) | DHODH | |
| SCHEMBL10075291 | 0.92 | SLC2A1 (0.34) | DHODHALDH1A1 | |
| SCHEMBL10075296 | 0.91 | DHODH (0.31) | DHODH | |
| SCHEMBL10075292 | 0.90 | CRHR1 (0.36) | ALDH1A1 | |
| SCHEMBL13085499 | 0.88 | GRIN1 (0.31) | NTRK1CHIAGRIN1GRIN2A | |
| SCHEMBL13085056 | 0.88 | IDO1 (0.32) | — | |
| SCHEMBL13085506 | 0.88 | NTRK1 (0.32) | DHODHNTRK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022112-A1 | USE OF ANTHRANILAMIDE DERIVATIVES FOR CONTROLLING INSECTS AND SPIDER MITES BY DRENCHING, SOIL MIXING, FURROW TREATMENT, DRIP APPLICATION, SOIL, STEM OR FLOWER INJECTION, IN HYDROPONIC SYSTEMS, BY PLANTING HOLE TREATMENT OR DIP APPLICATION, FLOATING OR SEEDBOX APPLICATION OR BY TREATING SEED, AND ALSO FOR ENHANCING THE STRESS TOLERANCE OF PLANTS TO ABIOTIC STRESS | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | US | disclosed |
| WO-2012010525-A2 | USE OF ANTHRANILIC ACID AMIDE DERIVATIVES FOR CONTROLLING INSECTS AND SPIDER MITES BY WATERING, MIXING WITH SOIL, DRENCH TREATMENT, DROPLET APPLICATION, INJECTION INTO THE SOIL, STEMS OR BLOSSOMS, IN HYDROPONIC SYSTEMS, BY TREATING THE PLANTING HOLE OR IMMERSION APPLICATION, FLOATING OR SEED BOX APPLICATION OR BY THE TREATMENT OF SEEDS, AND FOR INCREASING THE STRESS TOLERANCE IN PLANTS TO ABIOTIC STRESS | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | WO | disclosed |
| US-20120010073-A1 | Anthranilamides in combination with fungicides | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | US | disclosed |
| US-20110311503-A1 | Active ingredient combinations having insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010073-A1 | Anthranilamides in combination with fungicides | AADAC, ANTXR2, CYP51A1 | DHODH 815/4885NTRK1 4774/4885ALDH1A1 1960/4885 |
| US-20120022112-A1 | USE OF ANTHRANILAMIDE DERIVATIVES FOR CONTROLLING INSECTS AND SPIDER MITES BY DRENCHING, SOIL MIXING, FURROW TREATMENT, DRIP APPLICATION, SOIL, STEM OR FLOWER INJECTION, IN HYDROPONIC SYSTEMS, BY PLANTING HOLE TREATMENT OR DIP APPLICATION, FLOATING OR SEEDBOX APPLICATION OR BY TREATING SEED, AND ALSO FOR ENHANCING THE STRESS TOLERANCE OF PLANTS TO ABIOTIC STRESS | CDY1; CDY1B, DHX9, DHX29 | DHODH 265/4885NTRK1 3877/4885ALDH1A1 1757/4885 |
| US-20110311503-A1 | Active ingredient combinations having insecticidal and acaricidal properties | ACHE, ACAT1, ACAT2 | DHODH 1758/4885NTRK1 4722/4885ALDH1A1 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.