Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL469467 | 0.98 | AKR1C3 (0.57) | AKR1C3AKR1C2LMNACYP1A2CYP2D6 | |
| SCHEMBL469584 | 0.97 | AKR1C3 (0.56) | AKR1C3AKR1C2LMNACYP1A2CYP2D6 | |
| SCHEMBL469506 | 0.95 | AKR1C3 (0.58) | AKR1C3AKR1C2LMNACYP1A2CYP2D6 | |
| SCHEMBL469475 | 0.93 | AKR1C3 (0.58) | AKR1C3AKR1C2LMNACYP1A2CYP2D6 | |
| SCHEMBL456875 | 0.87 | AKR1C3 (0.60) | AKR1C3AKR1C2LMNACYP1A2CYP2D6 | |
| SCHEMBL456876 | 0.87 | AKR1C3 (0.60) | AKR1C3AKR1C2LMNACYP1A2CYP2D6 | |
| SCHEMBL8649132 | 0.77 | LMNA (0.69) | AKR1C3AKR1C2LMNACYP1A2CYP2D6 | |
| SCHEMBL9235971 | 0.76 | PTGS2 (0.74) | AKR1C3AKR1C2LMNACYP1A2CYP2D6 | |
| SCHEMBL10876035 | 0.76 | AKR1C3 (0.76) | AKR1C3AKR1C2LMNACYP1A2CYP2D6 | |
| SCHEMBL18271385 | 0.75 | AKR1C3 (0.82) | AKR1C3AKR1C2LMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160120995-A1 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | MEDWELL LAB LTD (IL) | 2016-05-05 | — | — | US | disclosed |
| US-20160120995-A1 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | MEDWELL LAB LTD (IL) | 2016-05-05 | — | — | US | disclosed |
| US-20130158070-A1 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | MEDWELL LABORATORIES LTD. (IL) | 2013-06-20 | — | — | US | disclosed |
| US-20130158070-A1 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | MEDWELL LABORATORIES LTD. (IL) | 2013-06-20 | — | — | US | disclosed |
| WO-2012032509-A2 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | MEDWELL LABORATORIES LTD. (IL) | 2012-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158070-A1 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | ALOX5, ALOX15B, ALOX15 | AKR1C3 888/4885AKR1C2 1177/4885LMNA 3256/4885 |
| US-20160120995-A1 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | ALOX5, ALOX15B, ALOX15 | AKR1C3 918/4885AKR1C2 1219/4885LMNA 3566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.