Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | CCR1 | P32246 | 4/20 | 0.46 |
| ▸ | CCR8 | P51685 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CCR5 | P51681 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30557034 | 0.76 | MMP2 (0.48) | KDM4EMAPTCCR1CCR8LMNA | |
| SCHEMBL26123221 | 0.76 | CCR1 (0.46) | KDM4EMAPTCCR1CCR8LMNA | |
| SCHEMBL3234181 | 0.76 | MMP2 (0.48) | KDM4EMAPTCCR1CCR8LMNA | |
| SCHEMBL30556846 | 0.76 | CCR1 (0.46) | KDM4EMAPTCCR1CCR8LMNA | |
| SCHEMBL29559557 | 0.76 | CCR1 (0.46) | KDM4EMAPTCCR1CCR8LMNA | |
| SCHEMBL17497064 | 0.76 | CCR1 (0.46) | KDM4EMAPTCCR1CCR8LMNA | |
| SCHEMBL19249169 | 0.76 | PDE4A (0.43) | KDM4EMAPTCCR1CCR8LMNA | |
| SCHEMBL10077957 | 0.76 | CCR1 (0.42) | KDM4EMAPTCCR1CCR8LMNA | |
| SCHEMBL9375947 | 0.75 | CCR1 (0.42) | KDM4EMAPTCCR1CCR8LMNA | |
| SCHEMBL17319744 | 0.73 | L3MBTL1 (0.48) | KDM4EMAPTCCR1CCR8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023180189-A1 | MPRO TARGETING ANTIVIRAL COMPOUNDS | EXSCIENTIA AI LIMITED (GB) | 2023-09-28 | — | — | WO | disclosed |
| US-11245078-B2 | Thermally activated delayed fluorescent material based on 9,10-dihydro-9,9-dimethylacridine analogues for prolonging device longevity | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2022-02-08 | — | — | US | disclosed |
| US-20200075868-A1 | Thermally Activated Delayed Fluorescent Material Based on 9,10-Dihydro-9,9-dimethylacridine Analogues for Prolonging Device Longevity | UNIV ARIZONA STATE (US) | 2020-03-05 | — | — | US | disclosed |
| US-10211411-B2 | Thermally activated delayed fluorescent material based on 9,10-dihydro-9,9-dimethylacridine analogues for prolonging device longevity | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2019-02-19 | — | — | US | disclosed |
| US-20170077420-A1 | Thermally Activated Delayed Fluorescent Material Based on 9,10-Dihydro-9,9-dimethylacridine Analogues for Prolonging Device Longevity | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2017-03-16 | — | — | US | disclosed |
| US-20160311871-A1 | RESISTANT MUTANT 90 kDA HEAT SHOCK PROTEIN | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2016-10-27 | — | — | US | disclosed |
| EP-3064582-A1 | RESISTANT MUTANT 90 kDA HEAT SHOCK PROTEIN | Taiho Pharmaceutical Co., Ltd. (JP) | 2016-09-07 | — | — | EP | disclosed |
| WO-2015050235-A1 | RESISTANT MUTANT 90 kDA HEAT SHOCK PROTEIN | 大鵬薬品工業株式会社 | 2015-04-09 | — | — | WO | disclosed |
| US-8575166-B2 | Phthalazine-containing antidiabetic compounds | MERCK SHARP & DOHME CORP. (US) | 2013-11-05 | — | — | US | disclosed |
| US-20120004234-A1 | PHTHALAZINE-CONTAINING ANTIDIABETIC COMPOUNDS | SCHERING CORPORATION (US) | 2012-01-05 | — | — | US | disclosed |
| WO-2010091176-A1 | PHTHALAZINE-CONTAINING ANTIDIABETIC COMPOUNDS | SCHERING CORPORATION (US) | 2010-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004234-A1 | PHTHALAZINE-CONTAINING ANTIDIABETIC COMPOUNDS | GPR119, FFAR2, FFAR1 | KDM4E 2154/4885MAPT 3132/4885CCR1 3731/4885 |
| US-20170077420-A1 | Thermally Activated Delayed Fluorescent Material Based on 9,10-Dihydro-9,9-dimethylacridine Analogues for Prolonging Device Longevity | HSPA9, CASP9, PARP9 | KDM4E 1943/4885MAPT 1400/4885CCR1 4378/4885 |
| US-20160311871-A1 | RESISTANT MUTANT 90 kDA HEAT SHOCK PROTEIN | HSP90AB1, HSP90AA1, HSP90AB2P | KDM4E 2950/4885MAPT 1891/4885CCR1 4072/4885 |
| US-11245078-B2 | Thermally activated delayed fluorescent material based on 9,10-dihydro-9,9-dimethylacridine analogues for prolonging device longevity | HSPA9, CASP9, PARP9 | KDM4E 1943/4885MAPT 1400/4885CCR1 4378/4885 |
| US-20200075868-A1 | Thermally Activated Delayed Fluorescent Material Based on 9,10-Dihydro-9,9-dimethylacridine Analogues for Prolonging Device Longevity | HSPA9, CASP9, PARP9 | KDM4E 1943/4885MAPT 1400/4885CCR1 4378/4885 |
| US-10211411-B2 | Thermally activated delayed fluorescent material based on 9,10-dihydro-9,9-dimethylacridine analogues for prolonging device longevity | HSPA9, CASP9, PARP9 | KDM4E 1902/4885MAPT 1403/4885CCR1 4352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.