SCHEMBL5037458

SCHEMBL5037458

O=CC(CCC1c2ccccc2-c2c(C(=O)O)cccc21)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
LMNA P02545 3/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MAPT P10636 1/20 0.42
HNF4A P41235 1/20 0.37
MYC P01106 1/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
GAA P10253 1/20 0.36
RAB9A P51151 1/20 0.36
GFER P55789 1/20 0.36
KMT2A Q03164 1/20 0.36
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
ACLY P53396 2/20 0.34
CYP1A2 P05177 1/20 0.34
TSHR P16473 1/20 0.34
FABP7 O15540 1/20 0.34
FABP5 Q01469 1/20 0.34
KDM4E B2RXH2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8092638 0.76 HNF4A (0.50) ALDH1A1LMNAL3MBTL1MAPTHNF4A
SCHEMBL10085227 0.72 ALDH1A1 (0.45) ALDH1A1LMNAL3MBTL1MAPTHNF4A
SCHEMBL1934919 0.70 ALDH1A1 (0.43) ALDH1A1LMNAL3MBTL1MAPTHNF4A
SCHEMBL9956780 0.70 ALDH1A1 (0.49) ALDH1A1LMNAL3MBTL1MAPTHNF4A
SCHEMBL7724549 0.69 ALDH1A1 (0.45) ALDH1A1LMNAL3MBTL1MAPTHNF4A
SCHEMBL16253851 0.68 KMT2A (0.51) ALDH1A1LMNAL3MBTL1MAPTMYC
SCHEMBL31670439 0.67 ALDH1A1 (0.51) ALDH1A1LMNAL3MBTL1MAPTHNF4A
SCHEMBL3552319 0.67 ALDH1A1 (0.51) ALDH1A1LMNAL3MBTL1MAPTHNF4A
SCHEMBL3552317 0.67 ALDH1A1 (0.51) ALDH1A1LMNAL3MBTL1MAPTHNF4A
SCHEMBL3552315 0.67 ALDH1A1 (0.51) ALDH1A1LMNAL3MBTL1MAPTHNF4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1896082-A2 CONJUGATES HAVING A DEGRADABLE LINKAGE AND POLYMERIC REAGENTS USEFUL IN PREPARING SUCH CONJUGATES Nektar Therapeutics AL, Corporation (US) 2008-03-12 EP disclosed
WO-2006138572-A2 CONJUGATES HAVING A DEGRADABLE LINKAGE AND POLYMERIC REAGENTS USEFUL IN PREPARING SUCH CONJUGATES NEKTAR THERAPEUTICS AL, CORPORATION (US) 2006-12-28 WO disclosed