Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2296334 | 0.83 | LOXL2 (0.47) | CYP4F2CYP4A11SMN1; SMN2NPC1KDM4E | |
| SCHEMBL14331820 | 0.79 | CYP3A4 (0.51) | SMN1; SMN2TP53ALDH1A1SLC7A5 | |
| SCHEMBL24341135 | 0.77 | SMN1; SMN2 (0.52) | CYP4F2CYP4A11SMN1; SMN2NPC1RAB9A | |
| SCHEMBL17386357 | 0.76 | CYP3A4 (0.50) | SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL7038941 | 0.76 | ALDH1A1 (0.52) | CYP4F2CYP4A11SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8233433 | 0.76 | LOXL2 (0.43) | CYP4F2CYP4A11SMN1; SMN2NPC1KDM4E | |
| SCHEMBL2289886 | 0.75 | MAOB (0.38) | RAB9AGAA | |
| SCHEMBL8240679 | 0.74 | ADRB2 (0.40) | CYP4F2CYP4A11KDM4EKMT2APTPRB | |
| SCHEMBL4113212 | 0.74 | CYP4F2 (0.76) | CYP4F2CYP4A11SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4014182 | 0.73 | CYP4F2 (0.59) | CYP4F2CYP4A11SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168821-B2 | Cyclopropylacetic acid derivatives and use thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-05-01 | — | — | US | disclosed |
| US-20090286882-A1 | Cyclopropylacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286882-A1 | Cyclopropylacetic Acid Derivatives and Use Thereof | PCCA, PPP2CA, HMGCR | CYP4F2 355/4885CYP4A11 225/4885SMN1; SMN2 3942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.