Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2296334 | 0.85 | LOXL2 (0.47) | ADRB2ADRB1ADRB3SNCACA12 | |
| SCHEMBL26427155 | 0.81 | ADRB2 (0.36) | ADRB2ADRB1ADRB3SNCASLC7A5 | |
| SCHEMBL2690871 | 0.80 | LDHA (0.53) | SLC7A5CA12CA1CA2CA9 | |
| SCHEMBL8233433 | 0.78 | LOXL2 (0.43) | ADRB2ADRB1ADRB3SNCACA12 | |
| SCHEMBL20168666 | 0.77 | SLC7A5 (0.38) | ADRB2ADRB1ADRB3SLC7A5CA12 | |
| SCHEMBL20179138 | 0.77 | SLC7A5 (0.38) | ADRB2ADRB1ADRB3SLC7A5CA12 | |
| SCHEMBL21578054 | 0.76 | SLC7A5 (0.39) | ADRB2ADRB1ADRB3SLC7A5CA12 | |
| SCHEMBL23710398 | 0.76 | TSHR (0.46) | ADRB2ADRB1ADRB3SNCATHRB | |
| SCHEMBL18873609 | 0.75 | TSHR (0.40) | ADRB2ADRB1ADRB3SLC7A5CA12 | |
| SCHEMBL15828913 | 0.75 | SLC7A5 (0.47) | ADRB3SLC7A5CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168821-B2 | Cyclopropylacetic acid derivatives and use thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-05-01 | — | — | US | disclosed |
| US-8168821-B2 | Cyclopropylacetic acid derivatives and use thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-05-01 | — | — | US | disclosed |
| US-20090286882-A1 | Cyclopropylacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2009-11-19 | — | — | US | disclosed |
| US-20090286882-A1 | Cyclopropylacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2009-11-19 | — | — | US | disclosed |
| CN-101346339-A | Cyclopropylacetic acid derivatives and use thereof | BAYER HEALTHCARE AG (DE) | 2009-01-14 | — | — | CN | disclosed |
| WO-2007045367-A1 | CYCLOPROPYLACETIC ACID DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286882-A1 | Cyclopropylacetic Acid Derivatives and Use Thereof | PCCA, PPP2CA, HMGCR | ADRB2 417/4885ADRB1 343/4885ADRB3 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.