SCHEMBL10086101

SCHEMBL10086101

CCCCNCCN(C)C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.61
CYP2C9 P11712 1/20 0.61
TSHR P16473 3/20 0.52
ALDH1A1 P00352 2/20 0.52
TDP1 Q9NUW8 1/20 0.50
DNM1 Q05193 5/20 0.48
PRMT3 O60678 1/20 0.43
CARM1 Q86X55 1/20 0.43
PRMT6 Q96LA8 1/20 0.43
PRMT1 Q99873 1/20 0.43
PRMT8 Q9NR22 1/20 0.43
PAOX Q6QHF9 1/20 0.41
MEN1 O00255 1/20 0.39
GLA P06280 1/20 0.39
KMT2A Q03164 1/20 0.39
ADH1B P00325 1/20 0.39
ADH1C P00326 1/20 0.39
ADH1A P07327 1/20 0.39
ADH7 P40394 1/20 0.39
KDM1A O60341 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13718039 0.92 TSHR (0.65) CYP2C19CYP2C9TSHRALDH1A1TDP1
SCHEMBL3237623 0.90 ALDH1A1 (0.62) CYP2C19CYP2C9TSHRALDH1A1TDP1
SCHEMBL20834938 0.90 ALDH1A1 (0.62) CYP2C19CYP2C9TSHRALDH1A1TDP1
SCHEMBL3798000 0.90 ALDH1A1 (0.62) CYP2C19CYP2C9TSHRALDH1A1TDP1
SCHEMBL7327027 0.90 ALDH1A1 (0.62) CYP2C19CYP2C9TSHRALDH1A1TDP1
SCHEMBL24728785 0.90 ALDH1A1 (0.62) CYP2C19CYP2C9TSHRALDH1A1TDP1
SCHEMBL11789511 0.90 ALDH1A1 (0.62) CYP2C19CYP2C9TSHRALDH1A1TDP1
SCHEMBL18402571 0.90 ALDH1A1 (0.62) CYP2C19CYP2C9TSHRALDH1A1TDP1
SCHEMBL31139789 0.90 ALDH1A1 (0.62) CYP2C19CYP2C9TSHRALDH1A1TDP1
SCHEMBL28571923 0.90 ALDH1A1 (0.62) CYP2C19CYP2C9TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11505562-B2 Process for the generation of metal-containing films BASF SE (DE) 2022-11-22 US disclosed
US-20210079025-A1 PROCESS FOR THE GENERATION OF METAL-CONTAINING FILMS WAYNE STATE UNIVERSITY 2021-03-18 US disclosed
US-20180163002-A1 ORGANOPOLYSILOXANE GRAFT POLYMER KAO CORPORATION (JP) 2018-06-14 US disclosed
US-9926409-B2 Organopolysiloxane graft polymer KAO CORPORATION (JP) 2018-03-27 US disclosed
US-9447122-B2 Arginase inhibitors and methods of use thereof ASTRAZENECA AB (SE) 2016-09-20 US disclosed
US-9351920-B2 Organopolysiloxane graft polymer KAO CORPORATION (JP) 2016-05-31 US disclosed
EP-2636674-B1 (AMIDE AMINO ALKANE) METAL COMPOUND AND METHOD OF PRODUCING METAL-CONTAINING THIN FILM USING SAID METAL COMPOUND UBE INDUSTRIES (JP) 2016-04-06 EP disclosed
US-20150374612-A1 ORGANOPOLYSILOXANE GRAFT POLYMER KAO CORPORATION (JP) 2015-12-31 US disclosed
WO-2015200680-A2 PRMT5 INHIBITORS AND USES THEREOF Epizyme, Inc. (US) 2015-12-30 WO disclosed
US-20150297498-A1 ORGANOPOLYSILOXANE GRAFT POLYMER KAO CORPORATION (JP) 2015-10-22 US disclosed
US-20150139931-A1 ORGANOPOLYSILOXANE GRAFT POLYMER KAO CORPORATION (JP) 2015-05-21 US disclosed
US-8894970-B2 Arginase inhibitors and methods of use thereof CORRIDOR PHARMACEUTICALS, INC. (US) 2014-11-25 US disclosed
US-8871304-B2 (Amide amino alkane) metal compound, method of manufacturing metal-containing thin film using said metal compound UBE INDUSTRIES, LTD. (JP) 2014-10-28 US disclosed
EP-2491037-B1 QUINAZOLIN-4(3H)-ONE DERIVATIVES USED AS PI3 KINASE INHIBITORS RESPIVERT LTD (GB) 2014-04-30 EP disclosed
US-20130273250-A1 (AMIDE AMINO ALKANE) METAL COMPOUND, METHOD OF MANUFACTURING METAL-CONTAINING THIN FILM USING SAID METAL COMPOUND UBE INDUSTRIES, LTD (JP) 2013-10-17 US disclosed
EP-2636674-A1 (AMIDE AMINO ALKANE) METAL COMPOUND, METHOD OF MANUFACTURING METAL-CONTAINING THIN FILM USING SAID METAL COMPOUND Ube Industries, Ltd. (JP) 2013-09-11 EP disclosed
EP-2121707-B1 ANTIVIRAL INDOLES ANGELETTI P IST RICHERCHE BIO (IT) 2012-12-05 EP disclosed
US-8101595-B2 Antiviral indoles Istituto di Ricerche di Biologia Molecolare P. Angletti SpA (IT) 2012-01-24 US disclosed
US-20100076046-A1 Antiviral Indoles ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) 2010-03-25 US disclosed
US-7179815-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2007-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11505562-B2 Process for the generation of metal-containing films NR2E1, NR0B2, NR2C2 CYP2C19 3196/4885CYP2C9 2678/4885TSHR 2865/4885
US-20150139931-A1 ORGANOPOLYSILOXANE GRAFT POLYMER IDUA, PIGS, FUCA1 CYP2C19 3022/4885CYP2C9 2684/4885TSHR 4116/4885
US-20210079025-A1 PROCESS FOR THE GENERATION OF METAL-CONTAINING FILMS NR2E1, NR0B2, NR2C2 CYP2C19 3196/4885CYP2C9 2678/4885TSHR 2865/4885
US-20100076046-A1 Antiviral Indoles IDO1, ZC3HAV1, IFNAR1 CYP2C19 1506/4885CYP2C9 1401/4885TSHR 1526/4885
US-20180163002-A1 ORGANOPOLYSILOXANE GRAFT POLYMER IDUA, PIGS, FUCA1 CYP2C19 3022/4885CYP2C9 2684/4885TSHR 4116/4885
US-20150374612-A1 ORGANOPOLYSILOXANE GRAFT POLYMER IDUA, PIGS, MPST CYP2C19 4005/4885CYP2C9 3612/4885TSHR 3902/4885
US-20150297498-A1 ORGANOPOLYSILOXANE GRAFT POLYMER IDUA, PIGS, GMNN CYP2C19 3798/4885CYP2C9 3859/4885TSHR 2848/4885
US-20130273250-A1 (AMIDE AMINO ALKANE) METAL COMPOUND, METHOD OF MANUFACTURING METAL-CONTAINING THIN FILM USING SAID METAL COMPOUND GNMT, SLC43A1, BET1 CYP2C19 4123/4885CYP2C9 3927/4885TSHR 1624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.