Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10088128 | 0.89 | CASP2 (0.53) | HPGDALDH1A1EPHX2CASP2NOD1 | |
| SCHEMBL10088106 | 0.85 | FAAH (0.36) | LMNAPKMHPGDALDH1A1EPHX2 | |
| SCHEMBL24818366 | 0.85 | NAMPT (0.52) | LMNAPKMHPGDNAMPTCNR1 | |
| SCHEMBL10345306 | 0.85 | NAMPT (0.52) | LMNAPKMHPGDNAMPTCNR1 | |
| SCHEMBL10345059 | 0.85 | NAMPT (0.52) | LMNAPKMHPGDNAMPTCNR1 | |
| SCHEMBL10660707 | 0.85 | NAMPT (0.52) | LMNAPKMHPGDNAMPTCNR1 | |
| SCHEMBL10359007 | 0.84 | FAAH (0.53) | CNR1EPHX2CASP2NOD1FAAH | |
| SCHEMBL10088088 | 0.84 | HPGD (0.42) | LMNAPKMHPGDCNR1ALDH1A1 | |
| SCHEMBL19239788 | 0.83 | ALDH1A1 (0.52) | LMNAPKMHPGDNAMPTCNR1 | |
| SCHEMBL23471810 | 0.83 | ALDH1A1 (0.50) | LMNAPKMHPGDNAMPTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8092782-B2 | Polybiotin compounds of magnetic resonance imaging and drug delivery | THE GENERAL HOSPITAL CORPORATION (US) | 2012-01-10 | — | — | US | disclosed |
| US-20090010845-A1 | Polybiotin Compounds of Magnetic Resonance Imaging and Drug Delivery | THE GENERAL HOSPITAL CORPORATION (US) | 2009-01-08 | — | — | US | disclosed |
| US-7438893-B2 | Polybiotin compounds for magnetic resonance imaging and drug delivery | MASSACHUSETTS GENERAL HOSPITAL (US) | 2008-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090010845-A1 | Polybiotin Compounds of Magnetic Resonance Imaging and Drug Delivery | BTD, BCAT1, BRD4 | LMNA 1434/4885PKM 2141/4885HPGD 2524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.