Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.50 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10088128 | 0.95 | CASP2 (0.53) | FAAHDNM1CASP2NOD1EPHX2 | |
| SCHEMBL10088127 | 0.88 | NOD1 (0.46) | FAAHDNM1NOD1EPHX2SMN1; SMN2 | |
| SCHEMBL10088105 | 0.84 | LMNA (0.44) | FAAHCASP2NOD1EPHX2CNR1 | |
| SCHEMBL23472179 | 0.82 | FAAH (0.61) | FAAHDNM1CASP2NOD1EPHX2 | |
| SCHEMBL25053064 | 0.81 | FAAH (0.55) | FAAHDNM1NOD1EPHX2MEN1 | |
| SCHEMBL18557505 | 0.81 | CASP2 (0.54) | FAAHDNM1CASP2NOD1EPHX2 | |
| SCHEMBL16860725 | 0.79 | NOD1 (0.73) | FAAHDNM1CASP2NOD1EPHX2 | |
| SCHEMBL10088131 | 0.79 | CASP2 (0.56) | FAAHDNM1CASP2NOD1EPHX2 | |
| SCHEMBL16860753 | 0.79 | NOD1 (0.73) | FAAHDNM1CASP2NOD1EPHX2 | |
| SCHEMBL194727 | 0.79 | GPR84 (0.54) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394311-A1 | RENIN INHIBITING PEPTIDES THAT CONTAIN AMINO AND HYDROXY DICARBOXYLIC ACIDS | THE UPJOHN COMPANY (US) | 1990-10-31 | — | — | EP | claimed |
| WO-1989004833-A1 | RENIN INHIBITING PEPTIDES THAT CONTAIN AMINO AND HYDROXY DICARBOXYLIC ACIDS | THE UPJOHN COMPANY (US) | 1989-06-01 | — | — | WO | claimed |