Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | ME2 | P23368 | 1/20 | 0.44 |
| ▸ | ME1 | P48163 | 1/20 | 0.44 |
| ▸ | ME3 | Q16798 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17432753 | 0.95 | ME2 (0.47) | BACE1NPC1RAB9AMAPTTP53 | |
| SCHEMBL17430475 | 0.89 | ALKBH3 (0.47) | NPC1RAB9AMAPTME2ME1 | |
| SCHEMBL17432766 | 0.88 | ME2 (0.44) | NR1H2NR1H3NPC1RAB9AMAPT | |
| SCHEMBL17432764 | 0.86 | ME2 (0.42) | NR1H2NR1H3NPC1RAB9AMAPT | |
| SCHEMBL17430478 | 0.85 | CYP19A1 (0.51) | NPC1RAB9AMAPTTSHRSMN1; SMN2 | |
| SCHEMBL10089222 | 0.85 | PTGS2 (0.47) | MAPTMEN1KMT2APDE4BKDM4E | |
| SCHEMBL14582098 | 0.84 | ALDH1A1 (0.49) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL10378529 | 0.83 | LSS (0.41) | RAB9AMAPTEGFR | |
| SCHEMBL17432762 | 0.83 | GSTP1 (0.53) | NPC1RAB9AMAPTSMN1; SMN2CYP19A1 | |
| SCHEMBL11209183 | 0.82 | NR1H2 (0.39) | BACE1NR1H2NR1H3MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704683-B1 | CHROMOPHORES WITH PERFLUOROALKYL SUBSTITUENTS | BASF SE (DE) | 2017-10-18 | — | — | EP | disclosed |
| US-9388206-B2 | Chromophores with perfluoroalkyl substituents | BASF SE (DE) | 2016-07-12 | — | — | US | disclosed |
| US-20140103635-A1 | CHROMOPHORES WITH PERFLUOROALKYL SUBSTITUENTS | BASF SE (DE) | 2014-04-17 | — | — | US | disclosed |
| US-6013811-A | Preparation process of benzodifuranone dyes | BASF AKTIENGESELLSCHAFT (DE) | 2000-01-11 | — | — | US | disclosed |
| EP-0888408-A1 | PREPARATION PROCESS OF BENZODIFURANONE DYES | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-07 | — | — | EP | disclosed |
| US-5717112-A | Benzofuranone and benzodifuranone compounds | ZENECA LIMITED (GB) | 1998-02-10 | — | — | US | disclosed |
| EP-0669922-B1 | BENZOFURANONES, BENZODIFURANTRIONES AND PROCESSES FOR THE PREPARATION OF BENZODIFURANDIONES | BASF AG (DE) | 1997-08-20 | — | — | EP | disclosed |
| WO-1997028221-A1 | PREPARATION PROCESS OF BENZODIFURANONE DYES | BASF AKTIENGESELLSCHAFT (DE) | 1997-08-07 | — | — | WO | disclosed |
| US-5625080-A | Benzodifurantrione compounds and process | ZENECA LIMITED (GB) | 1997-04-29 | — | — | US | disclosed |
| EP-0669922-A1 | BENZOFURANONE AND BENZODIFURANTRIONE DERIVATIVES AND PROCESS FOR THE PREPARATION OF BENZODIFURANONES. | ZENECA LTD (GB) | 1995-09-06 | — | — | EP | disclosed |
| WO-1994012501-A1 | BENZOFURANONE AND BENZODIFURANTRIONE DERIVATIVES AND PROCESS FOR THE PREPARATION OF BENZODIFURANONES | ZENECA LIMITED (GB) | 1994-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140103635-A1 | CHROMOPHORES WITH PERFLUOROALKYL SUBSTITUENTS | RBP4, RBP1, FABP5 | BACE1 4867/4885NR1H2 998/4885NR1H3 1161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.