Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 2/20 | 0.32 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13264903 | 0.99 | ALDH1A1 (0.36) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20767546 | 0.90 | ALDH1A1 (0.35) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL18386292 | 0.90 | ALDH1A1 (0.37) | ALDH1A1KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL881201 | 0.88 | ALDH1A1 (0.35) | ALDH1A1GAAS1PR3 | |
| SCHEMBL13264906 | 0.86 | CYP26B1 (0.35) | ALDH1A1GAAS1PR3 | |
| SCHEMBL17483208 | 0.86 | HDAC8 (0.36) | ALDH1A1CA1CA2KDM4EGAA | |
| SCHEMBL2721464 | 0.85 | P2RX3 (0.35) | ALDH1A1GAAS1PR3 | |
| SCHEMBL20776003 | 0.85 | MAPT (0.34) | ALDH1A1CA1CA2KDM4EGAA | |
| SCHEMBL560019 | 0.84 | CA2 (0.31) | CA2S1PR3 | |
| SCHEMBL15628865 | 0.83 | CYP26B1 (0.36) | ALDH1A1KDM4EGAAHSD17B10S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9791450-B2 | Fluorescent compounds | BIOTIUM, INC. (US) | 2017-10-17 | — | — | US | disclosed |
| EP-2223086-B2 | FLUORESCENT COMPOUNDS - LABELING DYES | BIOTIUM INC (US) | 2016-06-01 | — | — | EP | disclosed |
| US-20160033520-A1 | FLUORESCENT COMPOUNDS | BIOTIUM, INC. | 2016-02-04 | — | — | US | disclosed |
| US-20150330973-A1 | Kits for analysis of biological samples | ANASPEC INCORPORATED (US) | 2015-11-19 | — | — | US | disclosed |
| US-20150259535-A1 | Fluorescent dyes | ANASPEC INC (US) | 2015-09-17 | — | — | US | disclosed |
| US-9097667-B2 | Fluorescent compounds | BIOTIUM, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-8999690-B2 | Kits for analysis of biological samples | ANASPEC INCORPORATED (US) | 2015-04-07 | — | — | US | disclosed |
| US-8921543-B2 | Fluorescent dyes | ANASPEC INCORPORATED (US) | 2014-12-30 | — | — | US | disclosed |
| US-20130210113-A1 | SMALL MOLECULE DYE CONJUGATES | ANASPEC INCORPORATED (US) | 2013-08-15 | — | — | US | disclosed |
| EP-2223086-B1 | FLUORESCENT COMPOUNDS - LABELING DYES | BIOTIUM INC (US) | 2013-03-20 | — | — | EP | disclosed |
| US-20100022768-A1 | Contain chemically reactive carbocyanine dyes that are intramolecularly crosslinked between the 1-position and 3'-position, their bioconjugates | ANASPEC INC (US) | 2010-01-28 | — | — | US | disclosed |
| US-20090305410-A1 | FLUORESCENT COMPOUNDS | BIOTIUM, INC. (US) | 2009-12-10 | — | — | US | disclosed |
| US-20090258418-A1 | Contain chemically reactive carbocyanine dyes that are intramolecularly crosslinked between the 1-position and 3'-position, their bioconjugates | DIWU ZHENJUN | 2009-10-15 | — | — | US | disclosed |
| US-20090258418-A1 | Contain chemically reactive carbocyanine dyes that are intramolecularly crosslinked between the 1-position and 3'-position, their bioconjugates | DIWU ZHENJUN | 2009-10-15 | — | — | US | disclosed |
| US-20090215108-A1 | biochemical conjugate with a dye; biological substance peptide, protein, nucleotide, nucleic acid, carbohydrate, lipid, membrane or cell; detecting optical response upon use of an illumination source; use as luminescent probes valuable reagents for the analysis and separation of molecules and cells | DIWU ZHENJUN | 2009-08-27 | — | — | US | disclosed |
| US-20090215108-A1 | biochemical conjugate with a dye; biological substance peptide, protein, nucleotide, nucleic acid, carbohydrate, lipid, membrane or cell; detecting optical response upon use of an illumination source; use as luminescent probes valuable reagents for the analysis and separation of molecules and cells | DIWU ZHENJUN | 2009-08-27 | — | — | US | disclosed |
| US-20090156799-A1 | Methods of making dyes | DIWU ZHENJUN | 2009-06-18 | — | — | US | disclosed |
| US-20090156799-A1 | Methods of making dyes | DIWU ZHENJUN | 2009-06-18 | — | — | US | disclosed |
| US-7465810-B2 | Chemically reactive carbocyanine dyes that are intramolecularly connected or crosslinked between the 1-position and 3'-position by a polyamino acid linker; reduction of the ground state aggregation caused by steric hindrance of the crosslinking results in more fluorescent on proteins and nucleic acids | ANASPEC, INC. (US) | 2008-12-16 | — | — | US | disclosed |
| US-7465810-B2 | Chemically reactive carbocyanine dyes that are intramolecularly connected or crosslinked between the 1-position and 3'-position by a polyamino acid linker; reduction of the ground state aggregation caused by steric hindrance of the crosslinking results in more fluorescent on proteins and nucleic acids | ANASPEC, INC. (US) | 2008-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156799-A1 | Methods of making dyes | CBR3, CBR1, GLO1 | ALDH1A1 75/4885PSEN1 4076/4885PSEN2 4763/4885 |
| US-20130210113-A1 | SMALL MOLECULE DYE CONJUGATES | SLC7A5, LIG1, SLC43A1 | ALDH1A1 91/4885PSEN1 4037/4885PSEN2 4719/4885 |
| US-20090305410-A1 | FLUORESCENT COMPOUNDS | MKI67, CD68, CA5B | ALDH1A1 62/4885PSEN1 798/4885PSEN2 1424/4885 |
| US-20100022768-A1 | Contain chemically reactive carbocyanine dyes that are intramolecularly crosslinked between the 1-position and 3'-position, their bioconjugates | CBR3, RCN1, LIG1 | ALDH1A1 308/4885PSEN1 3686/4885PSEN2 4676/4885 |
| US-20090258418-A1 | Contain chemically reactive carbocyanine dyes that are intramolecularly crosslinked between the 1-position and 3'-position, their bioconjugates | CBR3, RCN1, LIG1 | ALDH1A1 308/4885PSEN1 3686/4885PSEN2 4676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.