SCHEMBL1009709

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3694287	0.90	DRD2 (0.49)	MAPTKIF11ALDH1A1HSD17B10ALOX15
	SCHEMBL1009369	0.86	PLAU (0.49)	MAPTKDM4ECA12CA1CA2
	SCHEMBL4433435	0.78	MAPT (0.50)	MAPTKDM4ECA12CA1CA2
	SCHEMBL379547	0.78	KDM4E (0.41)	MAPTKDM4ECA12CA1CA2
	SCHEMBL6984836	0.77	RAB9A (0.66)	MAPTKDM4EPLAUALDH1A1TP53
	SCHEMBL6984820	0.77	HTR6 (0.61)	MAPTKDM4ECA12CA1CA2
	SCHEMBL691153	0.76	MAPT (0.60)	MAPTKDM4ECA12CA1CA2
	SCHEMBL8386481	0.75	NPC1 (0.57)	MAPTALDH1A1HSD17B10ALOX15TDP1
	SCHEMBL12377130	0.75	NPC1 (0.62)	MAPTALDH1A1HSD17B10ALOX15TDP1
	SCHEMBL28951004	0.75	KDM4E (0.59)	MAPTKDM4ECA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.