SCHEMBL10098909

SCHEMBL10098909

Nc1cc(SCCO)c(Nc2ccc(CCO)cc2)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 6/20 0.49
▸ KMT2A Q03164 6/20 0.49
▸ MAPT P10636 4/20 0.49
▸ MAPK1 P28482 3/20 0.49
▸ NPSR1 Q6W5P4 3/20 0.49
▸ NPC1 O15118 3/20 0.49
▸ RAB9A P51151 3/20 0.49
▸ TDP1 Q9NUW8 3/20 0.49
▸ LMNA P02545 2/20 0.49
▸ L3MBTL1 Q9Y468 2/20 0.49
▸ S100A4 P26447 3/20 0.39
▸ CDC25A P30304 2/20 0.39
▸ CDC25B P30305 2/20 0.39
▸ KDM4E B2RXH2 2/20 0.39
▸ THRB P10828 2/20 0.39
▸ HPGD P15428 2/20 0.39
▸ MTOR P42345 2/20 0.39
▸ BLM P54132 2/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ CYP1A2 P05177 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL582631 0.81 MEN1 (0.57) MEN1KMT2AMAPTMAPK1NPSR1
SCHEMBL14011380 0.74 MEN1 (0.54) MEN1KMT2AMAPTMAPK1NPSR1
SCHEMBL375688 0.71 LMNA (0.87) MEN1KMT2AMAPTMAPK1NPSR1
SCHEMBL581829 0.69 MEN1 (0.62) MEN1KMT2AMAPTMAPK1NPSR1
SCHEMBL582954 0.69 MEN1 (0.62) MEN1KMT2AMAPTMAPK1NPSR1
SCHEMBL11877702 0.69 GNG2 (0.39) MEN1KMT2AMAPTMAPK1NPSR1
SCHEMBL5553577 0.68 MAPT (0.72) MEN1KMT2AMAPTMAPK1NPSR1
SCHEMBL582608 0.67 NPC1 (0.60) MEN1KMT2AMAPTMAPK1NPSR1
Alcohol SCHEMBL582632 0.67 MEN1 (0.60) MEN1KMT2AMAPTMAPK1NPSR1
SCHEMBL13135364 0.66 LMNA (0.77) MEN1KMT2AMAPTMAPK1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1984457-B1 BLUE COLOUR FILTERS WITH ENHANCED CONTRAST BASF SE (DE) 2013-01-09 — — EP disclosed
US-8148358-B2 Blue colour filters with enhanced contrast BASF SE (DE) 2012-04-03 — — US disclosed
US-8148358-B2 Blue colour filters with enhanced contrast BASF SE (DE) 2012-04-03 — — US disclosed
US-20100227199-A1 Blue Colour Filters with Enhanced Contrast CIBA CORPORATION 2010-09-09 — — US disclosed
US-20100227199-A1 Blue Colour Filters with Enhanced Contrast CIBA CORPORATION 2010-09-09 — — US disclosed
WO-2007093536-A2 BLUE COLOUR FILTERS WITH ENHANCED CONTRAST CIBA HOLDING INC. (CH) 2007-08-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100227199-A1 Blue Colour Filters with Enhanced Contrast NR1H4, NR1D1, NR1D2 MEN1 2699/4885KMT2A 3948/4885MAPT 3802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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