SCHEMBL18965716

SCHEMBL18965716

CNC(=O)C1CCC2C(=O)N(C3=CC=C(C4=CC=C(C)CC4)CC3)C(=O)C2C1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10098944 0.72 LMNA (0.49) TSHR
SCHEMBL10098932 0.72 CHRNB2 (0.36) TSHRMAPK1
SCHEMBL10098933 0.71 LMNA (0.51) TSHRMAPK1
SCHEMBL10098936 0.69 LMNA (0.52) TSHRMAPK1
SCHEMBL10098937 0.68 SMN1; SMN2 (0.52)
SCHEMBL10098942 0.67 TP53 (0.40) TSHR
SCHEMBL19423931 0.61
SCHEMBL10098934 0.59 ALDH1A1 (0.49)
SCHEMBL14879237 0.58 POLB (0.42) MAPK1
SCHEMBL13286467 0.57 ADAM17 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017169306-A1 METHOD FOR MANUFACTURING OPTICAL FILM コニカミノルタ株式会社 2017-10-05 WO disclosed
WO-2017169646-A1 POLYIMIDE FILM AND PRODUCTION METHOD THEREFOR コニカミノルタ株式会社 2017-10-05 WO disclosed
WO-2017169651-A1 DISPLAY DEVICE SURFACE MEMBER AND MANUFACTURING METHOD THEREFOR コニカミノルタ株式会社 2017-10-05 WO disclosed
WO-2017163698-A1 POLYIMIDE FILM AND PROCESS FOR PRODUCING SAME コニカミノルタ株式会社 2017-09-28 WO disclosed
WO-2017099041-A1 POLYIMIDE FILM, FLEXIBLE PRINTED BOARD, LED LIGHTING DEVICE ETC. コニカミノルタ株式会社 2017-06-15 WO disclosed