Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.40 |
| ▸ | CDK4 | P11802 | 3/20 | 0.38 |
| ▸ | CCND1 | P24385 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738190 | 0.81 | CYP11B1 (0.60) | KMT2ACYP11B1CYP11B2 | |
| SCHEMBL3193130 | 0.72 | CDK4 (0.51) | KMT2AHTR6PLAUCDK4CCND1 | |
| SCHEMBL10101653 | 0.71 | FNTA (0.46) | KMT2AHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL12544753 | 0.70 | CYP11B1 (0.72) | CYP11B1CYP11B2 | |
| SCHEMBL3177815 | 0.70 | HTR6 (0.65) | KMT2AHTR6HDAC1HDAC2HDAC10 | |
| SCHEMBL29509279 | 0.69 | HTR6 (0.73) | KMT2AHTR6HDAC1HDAC2HDAC10 | |
| SCHEMBL31021 | 0.69 | HTR6 (0.73) | KMT2AHTR6HDAC1HDAC2HDAC10 | |
| SCHEMBL29459650 | 0.68 | HTR6 (0.72) | KMT2AHTR6HDAC1HDAC2HDAC10 | |
| SCHEMBL2247137 | 0.68 | HTR6 (0.72) | KMT2AHTR6HDAC1HDAC2HDAC10 | |
| SCHEMBL28616092 | 0.67 | KMT2A (1.00) | KMT2AHTR6HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028940-A1 | FUNCTIONALLY SELECTIVE AZANITRILE ALPHA-2C ADRENORECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028940-A1 | FUNCTIONALLY SELECTIVE AZANITRILE ALPHA-2C ADRENORECEPTOR AGONISTS | ADRA2C, ADRB2, ADRA2A | KMT2A 899/4885HTR6 350/4885HDAC1 1412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.